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Structure and functionality in flavivirus NS-proteins: perspectives for drug design.
Bollati M, Alvarez K, Assenberg R, Baronti C, Canard B, Cook S, Coutard B, Decroly E, de Lamballerie X, Gould EA, Grard G, Grimes JM, Hilgenfeld R, Jansson AM, Malet H, Mancini EJ, Mastrangelo E, Mattevi A, Milani M, Moureau G, Neyts J, Owens RJ, Ren J, Selisko B, Speroni S, Steuber H, Stuart DI, Unge T, Bolognesi M. Bollati M, et al. Among authors: malet h. Antiviral Res. 2010 Aug;87(2):125-48. doi: 10.1016/j.antiviral.2009.11.009. Epub 2009 Nov 27. Antiviral Res. 2010. PMID: 19945487 Free PMC article. Review.
Expression, purification and crystallization of the SARS-CoV macro domain.
Malet H, Dalle K, Brémond N, Tocque F, Blangy S, Campanacci V, Coutard B, Grisel S, Lichière J, Lantez V, Cambillau C, Canard B, Egloff MP. Malet H, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Apr 1;62(Pt 4):405-8. doi: 10.1107/S1744309106009274. Epub 2006 Mar 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16582497 Free PMC article.
The flavivirus polymerase as a target for drug discovery.
Malet H, Massé N, Selisko B, Romette JL, Alvarez K, Guillemot JC, Tolou H, Yap TL, Vasudevan S, Lescar J, Canard B. Malet H, et al. Antiviral Res. 2008 Oct;80(1):23-35. doi: 10.1016/j.antiviral.2008.06.007. Epub 2008 Jul 9. Antiviral Res. 2008. PMID: 18611413 Review.
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket.
Malet H, Coutard B, Jamal S, Dutartre H, Papageorgiou N, Neuvonen M, Ahola T, Forrester N, Gould EA, Lafitte D, Ferron F, Lescar J, Gorbalenya AE, de Lamballerie X, Canard B. Malet H, et al. J Virol. 2009 Jul;83(13):6534-45. doi: 10.1128/JVI.00189-09. Epub 2009 Apr 22. J Virol. 2009. PMID: 19386706 Free PMC article.
Understanding the alphaviruses: recent research on important emerging pathogens and progress towards their control.
Gould EA, Coutard B, Malet H, Morin B, Jamal S, Weaver S, Gorbalenya A, Moureau G, Baronti C, Delogu I, Forrester N, Khasnatinov M, Gritsun T, de Lamballerie X, Canard B. Gould EA, et al. Among authors: malet h. Antiviral Res. 2010 Aug;87(2):111-24. doi: 10.1016/j.antiviral.2009.07.007. Epub 2009 Jul 16. Antiviral Res. 2010. PMID: 19616028 Free PMC article. Review.
33 results