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Exploring the dual effect of novel 1,4-diarylpyranopyrazoles as antiviral and anti-inflammatory for the management of SARS-CoV-2 and associated inflammatory symptoms.
Malebari AM, E A Ahmed H, Ihmaid SK, Omar AM, Muhammad YA, Althagfan SS, Aljuhani N, A A El-Sayed AA, Halawa AH, El-Tahir HM, Turkistani SA, Almaghrabi M, K B Aljohani A, El-Agrody AM, Abulkhair HS. Malebari AM, et al. Bioorg Chem. 2023 Jan;130:106255. doi: 10.1016/j.bioorg.2022.106255. Epub 2022 Nov 17. Bioorg Chem. 2023. PMID: 36403336 Free PMC article.
Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress.
Omar AM, El-Araby ME, Abdelghany TM, Safo MK, Ahmed MH, Boothello R, Patel BB, Abdel-Bakky MS, Malebari AM, Ahmed HEA, Elhaggar RS. Omar AM, et al. Among authors: malebari am. Bioorg Chem. 2020 Aug;101:103953. doi: 10.1016/j.bioorg.2020.103953. Epub 2020 May 25. Bioorg Chem. 2020. PMID: 32474179
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM. Ibrahim TS, et al. Among authors: malebari am. J Enzyme Inhib Med Chem. 2021 Dec;36(1):802-818. doi: 10.1080/14756366.2021.1899168. J Enzyme Inhib Med Chem. 2021. PMID: 33730937 Free PMC article.
A novel class of phenylpyrazolone-sulphonamides rigid synthetic anticancer molecules selectively inhibit the isoform IX of carbonic anhydrases guided by molecular docking and orbital analyses.
Khayat MT, Ahmed HEA, Omar AM, Muhammad YA, Mohammad KA, Malebari AM, Khayyat AN, Halawa AH, Abulkhair HS, Al-Karmalawy AA, Almaghrabi M, Alharbi M, Aljahdali AS, El-Agrody AM. Khayat MT, et al. Among authors: malebari am. J Biomol Struct Dyn. 2023;41(24):15243-15261. doi: 10.1080/07391102.2023.2188957. Epub 2023 Mar 13. J Biomol Struct Dyn. 2023. PMID: 36914238
37 results