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Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.
Herrera LJ, Brand S, Santos A, Nohara LL, Harrison J, Norcross NR, Thompson S, Smith V, Lema C, Varela-Ramirez A, Gilbert IH, Almeida IC, Maldonado RA. Herrera LJ, et al. Among authors: maldonado ra. PLoS Negl Trop Dis. 2016 Apr 29;10(4):e0004540. doi: 10.1371/journal.pntd.0004540. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27128971 Free PMC article.
Evaluation of α,β-unsaturated ketones as antileishmanial agents.
Vasquez MA, Iniguez E, Das U, Beverley SM, Herrera LJ, Dimmock JR, Maldonado RA. Vasquez MA, et al. Among authors: maldonado ra. Antimicrob Agents Chemother. 2015;59(6):3598-601. doi: 10.1128/AAC.04056-14. Epub 2015 Mar 23. Antimicrob Agents Chemother. 2015. PMID: 25801571 Free PMC article.
An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major.
Iniguez E, Schocker NS, Subramaniam K, Portillo S, Montoya AL, Al-Salem WS, Torres CL, Rodriguez F, Moreira OC, Acosta-Serrano A, Michael K, Almeida IC, Maldonado RA. Iniguez E, et al. Among authors: maldonado ra. PLoS Negl Trop Dis. 2017 Oct 25;11(10):e0006039. doi: 10.1371/journal.pntd.0006039. eCollection 2017 Oct. PLoS Negl Trop Dis. 2017. PMID: 29069089 Free PMC article.
Purification of Glycosylphosphatidylinositol-Anchored Mucins from Trypanosoma cruzi Trypomastigotes and Synthesis of α-Gal-Containing Neoglycoproteins: Application as Biomarkers for Reliable Diagnosis and Early Assessment of Chemotherapeutic Outcomes of Chagas Disease.
Ortega-Rodriguez U, Portillo S, Ashmus RA, Duran JA, Schocker NS, Iniguez E, Montoya AL, Zepeda BG, Olivas JJ, Karimi NH, Alonso-Padilla J, Izquierdo L, Pinazo MJ, de Noya BA, Noya O, Maldonado RA, Torrico F, Gascon J, Michael K, Almeida IC. Ortega-Rodriguez U, et al. Among authors: maldonado ra. Methods Mol Biol. 2019;1955:287-308. doi: 10.1007/978-1-4939-9148-8_22. Methods Mol Biol. 2019. PMID: 30868536 Free PMC article.
Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells.
Martínez A, Carreon T, Iniguez E, Anzellotti A, Sánchez A, Tyan M, Sattler A, Herrera L, Maldonado RA, Sánchez-Delgado RA. Martínez A, et al. Among authors: maldonado ra. J Med Chem. 2012 Apr 26;55(8):3867-77. doi: 10.1021/jm300070h. Epub 2012 Apr 9. J Med Chem. 2012. PMID: 22448965 Free PMC article.
52 results