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Cell-specific bioorthogonal tagging of glycoproteins.
Cioce A, Calle B, Rizou T, Lowery SC, Bridgeman VL, Mahoney KE, Marchesi A, Bineva-Todd G, Flynn H, Li Z, Tastan OY, Roustan C, Soro-Barrio P, Rafiee MR, Garza-Garcia A, Antonopoulos A, Wood TM, Keenan T, Both P, Huang K, Parmeggian F, Snijders AP, Skehel M, Kjær S, Fascione MA, Bertozzi CR, Haslam SM, Flitsch SL, Malaker SA, Malanchi I, Schumann B. Cioce A, et al. Among authors: malaker sa. Nat Commun. 2022 Oct 25;13(1):6237. doi: 10.1038/s41467-022-33854-0. Nat Commun. 2022. PMID: 36284108 Free PMC article.
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs.
Choi J, Wagner LJS, Timmermans SBPE, Malaker SA, Schumann B, Gray MA, Debets MF, Takashima M, Gehring J, Bertozzi CR. Choi J, et al. Among authors: malaker sa. J Am Chem Soc. 2019 Aug 28;141(34):13442-13453. doi: 10.1021/jacs.9b04695. Epub 2019 Aug 16. J Am Chem Soc. 2019. PMID: 31373799 Free PMC article.
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.
Schumann B, Malaker SA, Wisnovsky SP, Debets MF, Agbay AJ, Fernandez D, Wagner LJS, Lin L, Li Z, Choi J, Fox DM, Peh J, Gray MA, Pedram K, Kohler JJ, Mrksich M, Bertozzi CR. Schumann B, et al. Among authors: malaker sa. Mol Cell. 2020 Jun 4;78(5):824-834.e15. doi: 10.1016/j.molcel.2020.03.030. Epub 2020 Apr 22. Mol Cell. 2020. PMID: 32325029 Free PMC article.
Optimal Dissociation Methods Differ for N- and O-Glycopeptides.
Riley NM, Malaker SA, Driessen MD, Bertozzi CR. Riley NM, et al. Among authors: malaker sa. J Proteome Res. 2020 Aug 7;19(8):3286-3301. doi: 10.1021/acs.jproteome.0c00218. Epub 2020 Jun 28. J Proteome Res. 2020. PMID: 32500713 Free PMC article.
Targeted glycan degradation potentiates the anticancer immune response in vivo.
Gray MA, Stanczak MA, Mantuano NR, Xiao H, Pijnenborg JFA, Malaker SA, Miller CL, Weidenbacher PA, Tanzo JT, Ahn G, Woods EC, Läubli H, Bertozzi CR. Gray MA, et al. Among authors: malaker sa. Nat Chem Biol. 2020 Dec;16(12):1376-1384. doi: 10.1038/s41589-020-0622-x. Epub 2020 Aug 17. Nat Chem Biol. 2020. PMID: 32807964 Free PMC article.
Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation.
Debets MF, Tastan OY, Wisnovsky SP, Malaker SA, Angelis N, Moeckl LKR, Choi J, Flynn H, Wagner LJS, Bineva-Todd G, Antonopoulos A, Cioce A, Browne WM, Li Z, Briggs DC, Douglas HL, Hess GT, Agbay AJ, Roustan C, Kjaer S, Haslam SM, Snijders AP, Bassik MC, Moerner WE, Li VSW, Bertozzi CR, Schumann B. Debets MF, et al. Among authors: malaker sa. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25293-25301. doi: 10.1073/pnas.2007297117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989128 Free PMC article.
48 results