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A novel Bim-BH3-derived Bcl-XL inhibitor: biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity.
Ponassi R, Biasotti B, Tomati V, Bruno S, Poggi A, Malacarne D, Cimoli G, Salis A, Pozzi S, Miglino M, Damonte G, Cozzini P, Spyrakis F, Campanini B, Bagnasco L, Castagnino N, Tortolina L, Mumot A, Frassoni F, Daga A, Cilli M, Piccardi F, Monfardini I, Perugini M, Zoppoli G, D'Arrigo C, Pesenti R, Parodi S. Ponassi R, et al. Among authors: d arrigo c, malacarne d. Cell Cycle. 2008 Oct;7(20):3211-24. doi: 10.4161/cc.7.20.6830. Epub 2008 Oct 20. Cell Cycle. 2008. PMID: 18843207
Inhibition of a protein-protein interaction between INI1 and c-Myc by small peptidomimetic molecules inspired by Helix-1 of c-Myc: identification of a new target of potential antineoplastic interest.
Bagnasco L, Tortolina L, Biasotti B, Castagnino N, Ponassi R, Tomati V, Nieddu E, Stier G, Malacarne D, Parodi S. Bagnasco L, et al. Among authors: malacarne d. FASEB J. 2007 Apr;21(4):1256-63. doi: 10.1096/fj.06-7082com. Epub 2007 Jan 10. FASEB J. 2007. PMID: 17215484
Sequence specific peptidomimetic molecules inhibitors of a protein-protein interaction at the helix 1 level of c-Myc.
Nieddu E, Melchiori A, Pescarolo MP, Bagnasco L, Biasotti B, Licheri B, Malacarne D, Tortolina L, Castagnino N, Pasa S, Cimoli G, Avignolo C, Ponassi R, Balbi C, Patrone E, D'arrigo C, Barboro P, Vasile F, Orecchia P, Carnemolla B, Damonte G, Millo E, Palomba D, Fassina G, Mazzei M, Parodi S. Nieddu E, et al. Among authors: d arrigo c, malacarne d. FASEB J. 2005 Apr;19(6):632-4. doi: 10.1096/fj.04-2369fje. Epub 2005 Jan 25. FASEB J. 2005. PMID: 15671156
57 results