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Structural basis for activation of CB1 by an endocannabinoid analog.
Krishna Kumar K, Robertson MJ, Thadhani E, Wang H, Suomivuori CM, Powers AS, Ji L, Nikas SP, Dror RO, Inoue A, Makriyannis A, Skiniotis G, Kobilka B. Krishna Kumar K, et al. Among authors: makriyannis a. Nat Commun. 2023 May 9;14(1):2672. doi: 10.1038/s41467-023-37864-4. Nat Commun. 2023. PMID: 37160876 Free PMC article.
The neutral CB1 antagonist AM6527 reduces ethanol seeking, binge-like consumption, reinforcing, and withdrawal effects in male and female mice.
Raghav JG, Kumar H, Ji L, Vemuri K, Makriyannis A, Suh J, Leonard MZ, Dang V, Ty C, Marandola S, Kane N, Witt AS, Shaqour S, Miczek KA. Raghav JG, et al. Among authors: makriyannis a. Psychopharmacology (Berl). 2024 Mar;241(3):427-443. doi: 10.1007/s00213-023-06500-w. Epub 2023 Nov 25. Psychopharmacology (Berl). 2024. PMID: 38001264
Complex 33-beam simulated galactic cosmic radiation exposure impacts cognitive function and prefrontal cortex neurotransmitter networks in male mice.
Desai RI, Kangas BD, Luc OT, Solakidou E, Smith EC, Dawes MH, Ma X, Makriyannis A, Chatterjee S, Dayeh MA, Muñoz-Jaramillo A, Desai MI, Limoli CL. Desai RI, et al. Among authors: makriyannis a. Nat Commun. 2023 Nov 27;14(1):7779. doi: 10.1038/s41467-023-42173-x. Nat Commun. 2023. PMID: 38012180 Free PMC article.
Correction: Eid et al. Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. Molecules 2021, 26, 866.
Eid BG, Neamatallah T, Hanafy A, El-Bassossy HM, Binmahfouz L, Aldawsari HM, Hasan A, Abd El-Aziz G, Vemuri K, Makriyannis A. Eid BG, et al. Among authors: makriyannis a. Molecules. 2024 Feb 19;29(4):902. doi: 10.3390/molecules29040902. Molecules. 2024. PMID: 38398671 Free PMC article.
514 results