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Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
Schugar RC, Gliniak CM, Osborn LJ, Massey W, Sangwan N, Horak A, Banerjee R, Orabi D, Helsley RN, Brown AL, Burrows A, Finney C, Fung KK, Allen FM, Ferguson D, Gromovsky AD, Neumann C, Cook K, McMillan A, Buffa JA, Anderson JT, Mehrabian M, Goudarzi M, Willard B, Mak TD, Armstrong AR, Swanson G, Keshavarzian A, Garcia-Garcia JC, Wang Z, Lusis AJ, Hazen SL, Brown JM. Schugar RC, et al. Among authors: mak td. Elife. 2022 Jan 24;11:e63998. doi: 10.7554/eLife.63998. Elife. 2022. PMID: 35072627 Free PMC article.
A Single Human-Relevant Fast Food Meal Rapidly Reorganizes Metabolomic and Transcriptomic Signatures in a Gut Microbiota-Dependent Manner.
Osborn LJ, Orabi D, Goudzari M, Sangwan N, Banerjee R, Brown AL, Kadam A, Gromovsky AD, Linga P, Cresci GAM, Mak TD, Willard BB, Claesen J, Brown JM. Osborn LJ, et al. Among authors: mak td. Immunometabolism. 2021;3(4):e210029. doi: 10.20900/immunometab20210029. Epub 2021 Sep 18. Immunometabolism. 2021. PMID: 34804604 Free PMC article.
Crohn's disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome.
Jacobs JP, Goudarzi M, Lagishetty V, Li D, Mak T, Tong M, Ruegger P, Haritunians T, Landers C, Fleshner P, Vasiliauskas E, Ippoliti A, Melmed G, Shih D, Targan S, Borneman J, Fornace AJ Jr, McGovern DPB, Braun J. Jacobs JP, et al. Genome Med. 2022 Aug 15;14(1):91. doi: 10.1186/s13073-022-01099-7. Genome Med. 2022. PMID: 35971134 Free PMC article.
The effect of low dose rate on metabolomic response to radiation in mice.
Goudarzi M, Mak TD, Chen C, Smilenov LB, Brenner DJ, Fornace AJ. Goudarzi M, et al. Among authors: mak td. Radiat Environ Biophys. 2014 Nov;53(4):645-57. doi: 10.1007/s00411-014-0558-1. Epub 2014 Jul 22. Radiat Environ Biophys. 2014. PMID: 25047638 Free PMC article.
27 results