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Page 1
Reprogramming Cancer into Antigen-Presenting Cells as a Novel Immunotherapy.
Linde MH, Fan AC, Köhnke T, Trotman-Grant AC, Gurev SF, Phan P, Zhao F, Haddock NL, Nuno KA, Gars EJ, Stafford M, Marshall PL, Dove CG, Linde IL, Landberg N, Miller LP, Majzner RG, Zhang TY, Majeti R. Linde MH, et al. Among authors: majzner rg. Cancer Discov. 2023 May 4;13(5):1164-1185. doi: 10.1158/2159-8290.CD-21-0502. Cancer Discov. 2023. PMID: 36856575
Post-Transplantation Cyclophosphamide after Bone Marrow Transplantation Is Not Associated with an Increased Risk of Donor-Derived Malignancy.
Majzner RG, Mogri H, Varadhan R, Brown P, Cooke KR, Bolaños-Meade J, Swinnen L, Kanakry J, Luznik L, Jones RJ, Fuchs E, Ambinder R, Kasamon Y, Symons HJ. Majzner RG, et al. Biol Blood Marrow Transplant. 2017 Apr;23(4):612-617. doi: 10.1016/j.bbmt.2016.12.640. Epub 2017 Jan 3. Biol Blood Marrow Transplant. 2017. PMID: 28062216 Free PMC article.
T cell depletion utilizing CD34(+) stem cell selection and CD3(+) addback from unrelated adult donors in paediatric allogeneic stem cell transplantation recipients.
Geyer MB, Ricci AM, Jacobson JS, Majzner R, Duffy D, Van de Ven C, Ayello J, Bhatia M, Garvin JH Jr, George D, Satwani P, Harrison L, Morris E, Semidei-Pomales M, Schwartz J, Alobeid B, Baxter-Lowe LA, Cairo MS. Geyer MB, et al. Br J Haematol. 2012 Apr;157(2):205-19. doi: 10.1111/j.1365-2141.2012.09048.x. Epub 2012 Feb 8. Br J Haematol. 2012. PMID: 22313507 Free article. Clinical Trial.
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas.
Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M. Majzner RG, et al. Nature. 2022 Mar;603(7903):934-941. doi: 10.1038/s41586-022-04489-4. Epub 2022 Feb 7. Nature. 2022. PMID: 35130560 Free PMC article. Clinical Trial.
Pulmonary function after hematopoietic stem cell transplantation is significantly better in pediatric recipients following reduced toxicity compared with myeloablative conditioning.
Majzner R, Sandoval C, Dozor AJ, Jin Z, van de Ven C, Dalal R, Morris E, Harrison L, Wolownik K, Fabricatore S, Baxter-Lowe LA, Cairo MS. Majzner R, et al. Bone Marrow Transplant. 2016 Nov;51(11):1530-1532. doi: 10.1038/bmt.2016.172. Epub 2016 Jun 20. Bone Marrow Transplant. 2016. PMID: 27322849 No abstract available.
Tumor Antigen Escape from CAR T-cell Therapy.
Majzner RG, Mackall CL. Majzner RG, et al. Cancer Discov. 2018 Oct;8(10):1219-1226. doi: 10.1158/2159-8290.CD-18-0442. Epub 2018 Aug 22. Cancer Discov. 2018. PMID: 30135176 Review.
CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.
Majzner RG, Theruvath JL, Nellan A, Heitzeneder S, Cui Y, Mount CW, Rietberg SP, Linde MH, Xu P, Rota C, Sotillo E, Labanieh L, Lee DW, Orentas RJ, Dimitrov DS, Zhu Z, Croix BS, Delaidelli A, Sekunova A, Bonvini E, Mitra SS, Quezado MM, Majeti R, Monje M, Sorensen PHB, Maris JM, Mackall CL. Majzner RG, et al. Clin Cancer Res. 2019 Apr 15;25(8):2560-2574. doi: 10.1158/1078-0432.CCR-18-0432. Epub 2019 Jan 17. Clin Cancer Res. 2019. PMID: 30655315 Free PMC article.
Tuning the Antigen Density Requirement for CAR T-cell Activity.
Majzner RG, Rietberg SP, Sotillo E, Dong R, Vachharajani VT, Labanieh L, Myklebust JH, Kadapakkam M, Weber EW, Tousley AM, Richards RM, Heitzeneder S, Nguyen SM, Wiebking V, Theruvath J, Lynn RC, Xu P, Dunn AR, Vale RD, Mackall CL. Majzner RG, et al. Cancer Discov. 2020 May;10(5):702-723. doi: 10.1158/2159-8290.CD-19-0945. Epub 2020 Mar 19. Cancer Discov. 2020. PMID: 32193224 Free PMC article.
NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity.
Richards RM, Zhao F, Freitas KA, Parker KR, Xu P, Fan A, Sotillo E, Daugaard M, Oo HZ, Liu J, Hong WJ, Sorensen PH, Chang HY, Satpathy AT, Majzner RG, Majeti R, Mackall CL. Richards RM, et al. Among authors: majzner rg. Blood Cancer Discov. 2021 Sep 16;2(6):648-665. doi: 10.1158/2643-3230.BCD-20-0208. eCollection 2021 Nov. Blood Cancer Discov. 2021. PMID: 34778803 Free PMC article.
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication.
Theruvath J, Menard M, Smith BAH, Linde MH, Coles GL, Dalton GN, Wu W, Kiru L, Delaidelli A, Sotillo E, Silberstein JL, Geraghty AC, Banuelos A, Radosevich MT, Dhingra S, Heitzeneder S, Tousley A, Lattin J, Xu P, Huang J, Nasholm N, He A, Kuo TC, Sangalang ERB, Pons J, Barkal A, Brewer RE, Marjon KD, Vilches-Moure JG, Marshall PL, Fernandes R, Monje M, Cochran JR, Sorensen PH, Daldrup-Link HE, Weissman IL, Sage J, Majeti R, Bertozzi CR, Weiss WA, Mackall CL, Majzner RG. Theruvath J, et al. Among authors: majzner rg. Nat Med. 2022 Feb;28(2):333-344. doi: 10.1038/s41591-021-01625-x. Epub 2022 Jan 13. Nat Med. 2022. PMID: 35027753 Free PMC article.
47 results