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Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.
Caignard G, Leiva-Torres GA, Leney-Greene M, Charbonneau B, Dumaine A, Fodil-Cornu N, Pyzik M, Cingolani P, Schwartzentruber J, Dupaul-Chicoine J, Guo H, Saleh M, Veillette A, Lathrop M, Blanchette M, Majewski J, Pearson A, Vidal SM. Caignard G, et al. Among authors: majewski j. PLoS Pathog. 2013 Sep;9(9):e1003637. doi: 10.1371/journal.ppat.1003637. Epub 2013 Sep 12. PLoS Pathog. 2013. PMID: 24068938 Free PMC article.
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.
Kennedy JM, Fodil N, Torre S, Bongfen SE, Olivier JF, Leung V, Langlais D, Meunier C, Berghout J, Langat P, Schwartzentruber J, Majewski J, Lathrop M, Vidal SM, Gros P. Kennedy JM, et al. Among authors: majewski j. J Exp Med. 2014 Dec 15;211(13):2519-35. doi: 10.1084/jem.20140455. Epub 2014 Nov 17. J Exp Med. 2014. PMID: 25403443 Free PMC article.
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.
Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P. Torre S, et al. Among authors: majewski j. Nat Immunol. 2017 Jan;18(1):54-63. doi: 10.1038/ni.3581. Epub 2016 Oct 10. Nat Immunol. 2017. PMID: 27721430
What can exome sequencing do for you?
Majewski J, Schwartzentruber J, Lalonde E, Montpetit A, Jabado N. Majewski J, et al. J Med Genet. 2011 Sep;48(9):580-9. doi: 10.1136/jmedgenet-2011-100223. Epub 2011 Jul 5. J Med Genet. 2011. PMID: 21730106 Review.
Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia.
Xi Y, Honeywell C, Zhang D, Schwartzentruber J, Beaulieu CL, Tetreault M, Hartley T, Marton J, Vidal SM, Majewski J, Aravind L; Care4Rare Canada Consortium; Gollob M, Boycott KM, Gow RM. Xi Y, et al. Among authors: majewski j. Int J Cardiol. 2015 Apr 15;185:114-6. doi: 10.1016/j.ijcard.2015.03.130. Epub 2015 Mar 11. Int J Cardiol. 2015. PMID: 25791106 Free PMC article. No abstract available.
528 results