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Dissimilar Effect of P-Glycoprotein and Breast Cancer Resistance Protein Inhibition on the Distribution of Erlotinib to the Retina and Brain in Humans and Mice.
Biali ME, Auvity S, Cisternino S, Smirnova M, Hacker M, Zeitlinger M, Mairinger S, Tournier N, Bauer M, Langer O. Biali ME, et al. Among authors: mairinger s. Mol Pharm. 2023 Nov 6;20(11):5877-5887. doi: 10.1021/acs.molpharmaceut.3c00715. Epub 2023 Oct 26. Mol Pharm. 2023. PMID: 37883694 Free PMC article.
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
Traxl A, Mairinger S, Filip T, Sauberer M, Stanek J, Poschner S, Jäger W, Zoufal V, Novarino G, Tournier N, Bauer M, Wanek T, Langer O. Traxl A, et al. Among authors: mairinger s. Mol Pharm. 2019 Mar 4;16(3):1282-1293. doi: 10.1021/acs.molpharmaceut.8b01217. Epub 2019 Feb 11. Mol Pharm. 2019. PMID: 30694684
Measurement of Hepatic ABCB1 and ABCG2 Transport Activity with [11C]Tariquidar and PET in Humans and Mice.
Hernández Lozano I, Bauer M, Wulkersdorfer B, Traxl A, Philippe C, Weber M, Häusler S, Stieger B, Jäger W, Mairinger S, Wanek T, Hacker M, Zeitlinger M, Langer O. Hernández Lozano I, et al. Among authors: mairinger s. Mol Pharm. 2020 Jan 6;17(1):316-326. doi: 10.1021/acs.molpharmaceut.9b01060. Epub 2019 Dec 17. Mol Pharm. 2020. PMID: 31790256 Free article.
Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib.
Tournier N, Goutal S, Mairinger S, Hernández-Lozano I, Filip T, Sauberer M, Caillé F, Breuil L, Stanek J, Freeman AF, Novarino G, Truillet C, Wanek T, Langer O. Tournier N, et al. Among authors: mairinger s. J Cereb Blood Flow Metab. 2021 Jul;41(7):1634-1646. doi: 10.1177/0271678X20965500. Epub 2020 Oct 20. J Cereb Blood Flow Metab. 2021. PMID: 33081568 Free PMC article.
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs.
Hernández-Lozano I, Mairinger S, Filip T, Löbsch M, Stanek J, Kuntner C, Bauer M, Zeitlinger M, Hacker M, Helbich TH, Wanek T, Langer O. Hernández-Lozano I, et al. Among authors: mairinger s. Antimicrob Agents Chemother. 2023 Mar 16;67(3):e0149322. doi: 10.1128/aac.01493-22. Epub 2023 Feb 14. Antimicrob Agents Chemother. 2023. PMID: 36786609 Free PMC article.
63 results