Mai A - Search Results

1

Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response.

Cristalli C, Manara MC, Valente S, Pellegrini E, Bavelloni A, De Feo A, Blalock W, Di Bello E, Piñeyro D, Merkel A, Esteller M, Tirado OM, Mai A, Scotlandi K. Cristalli C, et al. Among authors: mai a. Front Endocrinol (Lausanne). 2022 May 31;13:876602. doi: 10.3389/fendo.2022.876602. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35712255 Free PMC article.

2

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Mai A, et al. Med Res Rev. 2005 May;25(3):261-309. doi: 10.1002/med.20024. Med Res Rev. 2005. PMID: 15717297 Review.

3

3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds.

Ragno R, Simeoni S, Valente S, Massa S, Mai A. Ragno R, et al. Among authors: mai a. J Chem Inf Model. 2006 May-Jun;46(3):1420-30. doi: 10.1021/ci050556b. J Chem Inf Model. 2006. PMID: 16711762

4

Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors.

Mai A, Massa S, Pezzi R, Valente S, Loidl P, Brosch G. Mai A, et al. Med Chem. 2005 May;1(3):245-54. doi: 10.2174/1573406053765431. Med Chem. 2005. PMID: 16787320

5

Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition.

Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Mai A, et al. ChemMedChem. 2006 Feb;1(2):225-37. doi: 10.1002/cmdc.200500015. ChemMedChem. 2006. PMID: 16892355

6

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors.

Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Mai A, et al. ChemMedChem. 2007 Jul;2(7):987-91. doi: 10.1002/cmdc.200700023. ChemMedChem. 2007. PMID: 17458842 No abstract available.

7

Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity.

Mai A, Valente S, Rotili D, Massa S, Botta G, Brosch G, Miceli M, Nebbioso A, Altucci L. Mai A, et al. Int J Biochem Cell Biol. 2007;39(7-8):1510-22. doi: 10.1016/j.biocel.2007.03.020. Epub 2007 Apr 4. Int J Biochem Cell Biol. 2007. PMID: 17482499

8

epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

Mai A, Cheng D, Bedford MT, Valente S, Nebbioso A, Perrone A, Brosch G, Sbardella G, De Bellis F, Miceli M, Altucci L. Mai A, et al. J Med Chem. 2008 Apr 10;51(7):2279-90. doi: 10.1021/jm701595q. Epub 2008 Mar 19. J Med Chem. 2008. PMID: 18348515

9

Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities.

Mai A, Perrone A, Nebbioso A, Rotili D, Valente S, Tardugno M, Massa S, De Bellis F, Altucci L. Mai A, et al. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2530-5. doi: 10.1016/j.bmcl.2008.03.055. Epub 2008 Mar 22. Bioorg Med Chem Lett. 2008. PMID: 18381238

10

HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2.

Scognamiglio A, Nebbioso A, Manzo F, Valente S, Mai A, Altucci L. Scognamiglio A, et al. Among authors: mai a. Biochim Biophys Acta. 2008 Oct;1783(10):2030-8. doi: 10.1016/j.bbamcr.2008.07.007. Epub 2008 Jul 22. Biochim Biophys Acta. 2008. PMID: 18691615 Free article.

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