Mai A - Search Results

1

Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation.

Zwergel C, Fioravanti R, Stazi G, Sarno F, Battistelli C, Romanelli A, Nebbioso A, Mendes E, Paulo A, Strippoli R, Tripodi M, Pechalrieu D, Arimondo PB, De Luca T, Del Bufalo D, Trisciuoglio D, Altucci L, Valente S, Mai A. Zwergel C, et al. Among authors: mai a. Cancers (Basel). 2020 Feb 14;12(2):447. doi: 10.3390/cancers12020447. Cancers (Basel). 2020. PMID: 32075099 Free PMC article.

2

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.

Mai A, Massa S, Cerbara I, Valente S, Ragno R, Bottoni P, Scatena R, Loidl P, Brosch G. Mai A, et al. J Med Chem. 2004 Feb 26;47(5):1098-109. doi: 10.1021/jm030990+. J Med Chem. 2004. PMID: 14971890

Previous SAR studies (Part 1: Mai, A.; et al. J. Med. Chem. 2003, 46, 512-524) performed on some portions (pyrrole-C4, pyrrole-N1, and hydroxamate group) of 3-(4-benzoyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamide (1a) highlighted its 4-phenylacetyl (1b) and 4- …

Previous SAR studies (Part 1: Mai, A.; et al. J. Med. Chem. 2003, 46, 512-524) performed on some portions (pyrrole-C4, pyrrole …

3

3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies.

Ragno R, Mai A, Massa S, Cerbara I, Valente S, Bottoni P, Scatena R, Jesacher F, Loidl P, Brosch G. Ragno R, et al. Among authors: mai a. J Med Chem. 2004 Mar 11;47(6):1351-9. doi: 10.1021/jm031036f. J Med Chem. 2004. PMID: 14998325

4

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Mai A, et al. Med Res Rev. 2005 May;25(3):261-309. doi: 10.1002/med.20024. Med Res Rev. 2005. PMID: 15717297 Review.

5

Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.

Mai A, Massa S, Pezzi R, Simeoni S, Rotili D, Nebbioso A, Scognamiglio A, Altucci L, Loidl P, Brosch G. Mai A, et al. J Med Chem. 2005 May 5;48(9):3344-53. doi: 10.1021/jm049002a. J Med Chem. 2005. PMID: 15857140

6

3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds.

Ragno R, Simeoni S, Valente S, Massa S, Mai A. Ragno R, et al. Among authors: mai a. J Chem Inf Model. 2006 May-Jun;46(3):1420-30. doi: 10.1021/ci050556b. J Chem Inf Model. 2006. PMID: 16711762

7

3-(1H-pyrrol-2-yl)-2-oxazolidinones as novel monoamine oxidase type A inhibitors.

Mai A, Artico M, Valente S, Sbardella G, Turini P, Befani O, Vedova LD, Agostinelli E. Mai A, et al. Med Chem. 2005 Mar;1(2):117-24. doi: 10.2174/1573406053175247. Med Chem. 2005. PMID: 16787307

8

Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors.

Mai A, Massa S, Pezzi R, Valente S, Loidl P, Brosch G. Mai A, et al. Med Chem. 2005 May;1(3):245-54. doi: 10.2174/1573406053765431. Med Chem. 2005. PMID: 16787320

9

Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition.

Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Mai A, et al. ChemMedChem. 2006 Feb;1(2):225-37. doi: 10.1002/cmdc.200500015. ChemMedChem. 2006. PMID: 16892355

10

Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors.

Mai A, Massa S, Rotili D, Simeoni S, Ragno R, Botta G, Nebbioso A, Miceli M, Altucci L, Brosch G. Mai A, et al. J Med Chem. 2006 Oct 5;49(20):6046-56. doi: 10.1021/jm0605536. J Med Chem. 2006. PMID: 17004718

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

588 results

Search Page