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Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer.
Ryu JR, Ahuja S, Arnold CR, Potts KG, Mishra A, Yang Q, Sargurupremraj M, Mahoney DJ, Seshadri S, Debette S, Childs SJ. Ryu JR, et al. Among authors: mahoney dj. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2121333119. doi: 10.1073/pnas.2121333119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994645 Free PMC article.
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.
Taha Z, Arulanandam R, Maznyi G, Godbout E, Carter-Timofte ME, Kurmasheva N, Reinert LS, Chen A, Crupi MJF, Boulton S, Laroche G, Phan A, Rezaei R, Alluqmani N, Jirovec A, Acal A, Fekete EEF, Singaravelu R, Petryk J, Idorn M, Potts KG, Todesco H, John C, Mahoney DJ, Ilkow CS, Giguère P, Alain T, Côté M, Paludan SR, Olagnier D, Bell JC, Azad T, Diallo JS. Taha Z, et al. Among authors: mahoney dj. Mol Ther. 2022 Sep 7;30(9):2998-3016. doi: 10.1016/j.ymthe.2022.04.025. Epub 2022 May 6. Mol Ther. 2022. PMID: 35526097 Free PMC article.
Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.
Boulton S, Poutou J, Martin NT, Azad T, Singaravelu R, Crupi MJF, Jamieson T, He X, Marius R, Petryk J, Tanese de Souza C, Austin B, Taha Z, Whelan J, Khan ST, Pelin A, Rezaei R, Surendran A, Tucker S, Fekete EEF, Dave J, Diallo JS, Auer R, Angel JB, Cameron DW, Cailhier JF, Lapointe R, Potts K, Mahoney DJ, Bell JC, Ilkow CS. Boulton S, et al. Among authors: mahoney dj. Mol Ther. 2022 May 4;30(5):1885-1896. doi: 10.1016/j.ymthe.2021.10.008. Epub 2021 Oct 20. Mol Ther. 2022. PMID: 34687845 Free PMC article.
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma.
Johnston MJ, Nikolic A, Ninkovic N, Guilhamon P, Cavalli FMG, Seaman S, Zemp FJ, Lee J, Abdelkareem A, Ellestad K, Murison A, Kushida MM, Coutinho FJ, Ma Y, Mungall AJ, Moore R, Marra MA, Taylor MD, Dirks PB, Pugh TJ, Morrissy S, St Croix B, Mahoney DJ, Lupien M, Gallo M. Johnston MJ, et al. Among authors: mahoney dj. Genome Res. 2019 Aug;29(8):1211-1222. doi: 10.1101/gr.246520.118. Epub 2019 Jun 27. Genome Res. 2019. PMID: 31249064 Free PMC article.
Smac mimetics and innate immune stimuli synergize to promote tumor death.
Beug ST, Tang VA, LaCasse EC, Cheung HH, Beauregard CE, Brun J, Nuyens JP, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney DJ, Ilkow C, Le Boeuf F, Bell JC, Korneluk RG. Beug ST, et al. Among authors: mahoney dj. Nat Biotechnol. 2014 Feb;32(2):182-90. doi: 10.1038/nbt.2806. Epub 2014 Jan 26. Nat Biotechnol. 2014. PMID: 24463573 Free PMC article.
Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death.
Mahoney DJ, Lefebvre C, Allan K, Brun J, Sanaei CA, Baird S, Pearce N, Grönberg S, Wilson B, Prakesh M, Aman A, Isaac M, Mamai A, Uehling D, Al-Awar R, Falls T, Alain T, Stojdl DF. Mahoney DJ, et al. Cancer Cell. 2011 Oct 18;20(4):443-56. doi: 10.1016/j.ccr.2011.09.005. Cancer Cell. 2011. PMID: 22014571 Free article.
Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, Lacasse EC, Waring J, Korneluk RG. Mahoney DJ, et al. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11778-83. doi: 10.1073/pnas.0711122105. Epub 2008 Aug 12. Proc Natl Acad Sci U S A. 2008. PMID: 18697935 Free PMC article.
Visualizing Oncolytic Virus-Host Interactions in Live Mice Using Intravital Microscopy.
Naumenko V, Van S, Dastidar H, Kim DS, Kim SJ, Zeng Z, Deniset J, Lau A, Zhang C, Macia N, Heyne B, Jenne CN, Mahoney DJ. Naumenko V, et al. Among authors: mahoney dj. Mol Ther Oncolytics. 2018 Jul 14;10:14-27. doi: 10.1016/j.omto.2018.06.001. eCollection 2018 Sep 28. Mol Ther Oncolytics. 2018. PMID: 30073187 Free PMC article.
96 results