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The KrasG12D;Trp53fl/fl murine model of undifferentiated pleomorphic sarcoma is macrophage dense, lymphocyte poor, and resistant to immune checkpoint blockade.
Hildebrand KM, Singla AK, McNeil R, Marritt KL, Hildebrand KN, Zemp F, Rajwani J, Itani D, Bose P, Mahoney DJ, Jirik FR, Monument MJ. Hildebrand KM, et al. Among authors: mahoney dj. PLoS One. 2021 Jul 9;16(7):e0253864. doi: 10.1371/journal.pone.0253864. eCollection 2021. PLoS One. 2021. PMID: 34242269 Free PMC article.
Author Correction: Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms.
Kim DS, Dastidar H, Zhang C, Zemp FJ, Lau K, Ernst M, Rakic A, Sikdar S, Rajwani J, Naumenko V, Balce DR, Ewanchuk BW, Tailor P, Yates RM, Jenne C, Gafuik C, Mahoney DJ. Kim DS, et al. Among authors: mahoney dj. Nat Commun. 2018 May 24;9(1):2109. doi: 10.1038/s41467-018-04597-8. Nat Commun. 2018. PMID: 29799008 Free PMC article.
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma.
Johnston MJ, Nikolic A, Ninkovic N, Guilhamon P, Cavalli FMG, Seaman S, Zemp FJ, Lee J, Abdelkareem A, Ellestad K, Murison A, Kushida MM, Coutinho FJ, Ma Y, Mungall AJ, Moore R, Marra MA, Taylor MD, Dirks PB, Pugh TJ, Morrissy S, St Croix B, Mahoney DJ, Lupien M, Gallo M. Johnston MJ, et al. Among authors: mahoney dj. Genome Res. 2019 Aug;29(8):1211-1222. doi: 10.1101/gr.246520.118. Epub 2019 Jun 27. Genome Res. 2019. PMID: 31249064 Free PMC article.
Smac mimetics and innate immune stimuli synergize to promote tumor death.
Beug ST, Tang VA, LaCasse EC, Cheung HH, Beauregard CE, Brun J, Nuyens JP, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney DJ, Ilkow C, Le Boeuf F, Bell JC, Korneluk RG. Beug ST, et al. Among authors: mahoney dj. Nat Biotechnol. 2014 Feb;32(2):182-90. doi: 10.1038/nbt.2806. Epub 2014 Jan 26. Nat Biotechnol. 2014. PMID: 24463573 Free PMC article.
The complex interplay between neutrophils and cancer.
Rakic A, Beaudry P, Mahoney DJ. Rakic A, et al. Among authors: mahoney dj. Cell Tissue Res. 2018 Mar;371(3):517-529. doi: 10.1007/s00441-017-2777-7. Epub 2018 Feb 9. Cell Tissue Res. 2018. PMID: 29427051 Review.
96 results