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Page 1
Comment faire évoluer le paradigme du développement clinique et son découpage en phases I, II, III.
Therapie. 2011 Jul-Aug;66(4):327-30. doi: 10.2515/therapie/2011043.
Therapie. 2011.
PMID: 27392459
French.
No abstract available.
Les comparateurs (médicamenteux et non médicamenteux) pour l'autorisation de mise sur le marché, pour la santé publique, pour les payeurs et au niveau européen.
Berdaï D, Hotton JM, Lechat P; les participants à la Table Ronde n°1 de Giens XXV.
Berdaï D, et al.
Therapie. 2010 Jul-Aug;65(4):323-8. doi: 10.2515/therapie/2010032.
Therapie. 2010.
PMID: 27393111
French.
No abstract available.
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Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice.
Drouin A, Gendron ME, Thorin E, Gillis MA, Mahlberg-Gaudin F, Tardif JC.
Drouin A, et al. Among authors: mahlberg gaudin f.
Br J Pharmacol. 2008 Jun;154(4):749-57. doi: 10.1038/bjp.2008.116. Epub 2008 Apr 14.
Br J Pharmacol. 2008.
PMID: 18414390
Free PMC article.
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Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure.
Mulder P, Barbier S, Chagraoui A, Richard V, Henry JP, Lallemand F, Renet S, Lerebours G, Mahlberg-Gaudin F, Thuillez C.
Mulder P, et al. Among authors: mahlberg gaudin f.
Circulation. 2004 Apr 6;109(13):1674-9. doi: 10.1161/01.CIR.0000118464.48959.1C. Epub 2004 Feb 23.
Circulation. 2004.
PMID: 14981003
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Preservation of coronary reserve by ivabradine-induced reduction in heart rate in infarcted rats is associated with decrease in perivascular collagen.
Dedkov EI, Zheng W, Christensen LP, Weiss RM, Mahlberg-Gaudin F, Tomanek RJ.
Dedkov EI, et al. Among authors: mahlberg gaudin f.
Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H590-8. doi: 10.1152/ajpheart.00047.2007. Epub 2007 Mar 23.
Am J Physiol Heart Circ Physiol. 2007.
PMID: 17384136
Free article.
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How to improve the clinical development paradigm and its division into phases I, II and III.
Bamberger M, Moore N, Lechat P; participants of Round Table N° 3 of Giens XXVI.
Bamberger M, et al.
Therapie. 2011 Jul-Aug;66(4):331-4, 327-30. doi: 10.2515/therapie/2011046. Epub 2011 Aug 19.
Therapie. 2011.
PMID: 21851796
Free article.
English, French.
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Comparators (medicinal and non medicinal) for marketing authorization, for public health, for payers and at the European level.
Berdaï D, Hotton JM, Lechat P; participates of Round Table n° 1 Giens XXV.
Berdaï D, et al.
Therapie. 2010 Jul-Aug;65(4):329-34. doi: 10.2515/therapie/2010035. Epub 2010 Sep 21.
Therapie. 2010.
PMID: 20854755
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