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Page 1
The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma.
Vora P, Venugopal C, Salim SK, Tatari N, Bakhshinyan D, Singh M, Seyfrid M, Upreti D, Rentas S, Wong N, Williams R, Qazi MA, Chokshi C, Ding A, Subapanditha M, Savage N, Mahendram S, Ford E, Adile AA, McKenna D, McFarlane N, Huynh V, Wylie RG, Pan J, Bramson J, Hope K, Moffat J, Singh S. Vora P, et al. Among authors: mahendram s. Cell Stem Cell. 2020 Jun 4;26(6):832-844.e6. doi: 10.1016/j.stem.2020.04.008. Epub 2020 May 27. Cell Stem Cell. 2020. PMID: 32464096 Free article.
Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells.
Venugopal C, Hallett R, Vora P, Manoranjan B, Mahendram S, Qazi MA, McFarlane N, Subapanditha M, Nolte SM, Singh M, Bakhshinyan D, Garg N, Vijayakumar T, Lach B, Provias JP, Reddy K, Murty NK, Doble BW, Bhatia M, Hassell JA, Singh SK. Venugopal C, et al. Among authors: mahendram s. Clin Cancer Res. 2015 Dec 1;21(23):5324-37. doi: 10.1158/1078-0432.CCR-14-3147. Epub 2015 Jul 7. Clin Cancer Res. 2015. PMID: 26152745
Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.
Vora P, Seyfrid M, Venugopal C, Qazi MA, Salim S, Isserlin R, Subapanditha M, O'Farrell E, Mahendram S, Singh M, Bakhshinyan D, Chokshi C, McFarlane N, Dvorkin-Gheva A, Brown KR, Murty N, Moffat J, Bader GD, Singh SK. Vora P, et al. Among authors: mahendram s. J Neurooncol. 2019 Jul;143(3):417-428. doi: 10.1007/s11060-019-03192-1. Epub 2019 May 21. J Neurooncol. 2019. PMID: 31115870
CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence.
Garg N, Bakhshinyan D, Venugopal C, Mahendram S, Rosa DA, Vijayakumar T, Manoranjan B, Hallett R, McFarlane N, Delaney KH, Kwiecien JM, Arpin CC, Lai PS, Gómez-Biagi RF, Ali AM, de Araujo ED, Ajani OA, Hassell JA, Gunning PT, Singh SK. Garg N, et al. Among authors: mahendram s. Oncogene. 2017 Feb 2;36(5):606-617. doi: 10.1038/onc.2016.235. Epub 2016 Oct 24. Oncogene. 2017. PMID: 27775079 Free PMC article.
STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation.
Singh M, Garg N, Venugopal C, Hallett R, Tokar T, McFarlane N, Mahendram S, Bakhshinyan D, Manoranjan B, Vora P, Qazi M, Arpin CC, Page B, Haftchenary S, Rosa DA, Lai PS, Gómez-Biagi RF, Ali AM, Lewis A, Geletu M, Murty NK, Hassell JA, Jurisica I, Gunning PT, Singh SK. Singh M, et al. Among authors: mahendram s. Oncotarget. 2015 Sep 29;6(29):27461-77. doi: 10.18632/oncotarget.4742. Oncotarget. 2015. PMID: 26314961 Free PMC article.
The identification of human pituitary adenoma-initiating cells.
Manoranjan B, Mahendram S, Almenawer SA, Venugopal C, McFarlane N, Hallett R, Vijayakumar T, Algird A, Murty NK, Sommer DD, Provias JP, Reddy K, Singh SK. Manoranjan B, et al. Among authors: mahendram s. Acta Neuropathol Commun. 2016 Nov 28;4(1):125. doi: 10.1186/s40478-016-0394-4. Acta Neuropathol Commun. 2016. PMID: 27894339 Free PMC article.
RNAi screen identifies essential regulators of human brain metastasis-initiating cells.
Singh M, Venugopal C, Tokar T, Brown KR, McFarlane N, Bakhshinyan D, Vijayakumar T, Manoranjan B, Mahendram S, Vora P, Qazi M, Dhillon M, Tong A, Durrer K, Murty N, Hallet R, Hassell JA, Kaplan DR, Cutz JC, Jurisica I, Moffat J, Singh SK. Singh M, et al. Among authors: mahendram s. Acta Neuropathol. 2017 Dec;134(6):923-940. doi: 10.1007/s00401-017-1757-z. Epub 2017 Aug 1. Acta Neuropathol. 2017. PMID: 28766011
BMI1 is a therapeutic target in recurrent medulloblastoma.
Bakhshinyan D, Venugopal C, Adile AA, Garg N, Manoranjan B, Hallett R, Wang X, Mahendram S, Vora P, Vijayakumar T, Subapanditha M, Singh M, Kameda-Smith MM, Qazi M, McFarlane N, Mann A, Ajani OA, Yarascavitch B, Ramaswamy V, Farooq H, Morrissy S, Cao L, Sydorenko N, Baiazitov R, Du W, Sheedy J, Weetall M, Moon YC, Lee CS, Kwiecien JM, Delaney KH, Doble B, Cho YJ, Mitra S, Kaplan D, Taylor MD, Davis TW, Singh SK. Bakhshinyan D, et al. Among authors: mahendram s. Oncogene. 2019 Mar;38(10):1702-1716. doi: 10.1038/s41388-018-0549-9. Epub 2018 Oct 22. Oncogene. 2019. PMID: 30348991
Brain metastasis-initiating cells: survival of the fittest.
Singh M, Manoranjan B, Mahendram S, McFarlane N, Venugopal C, Singh SK. Singh M, et al. Among authors: mahendram s. Int J Mol Sci. 2014 May 22;15(5):9117-33. doi: 10.3390/ijms15059117. Int J Mol Sci. 2014. PMID: 24857921 Free PMC article. Review.
14 results