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ORMDL MISLOCALIZATION BY IMPAIRED AUTOPHAGY IN NIEMANN-PICK TYPE C DISEASE LEADS TO INCREASED DE NOVO SPHINGOLIPID BIOSYNTHESIS.
J Lipid Res. 2024 May 6:100556. doi: 10.1016/j.jlr.2024.100556. Online ahead of print.
J Lipid Res. 2024.
PMID: 38719150
Free article.
Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Xie T, Liu P, Wu X, Dong F, Zhang Z, Yue J, Mahawar U, Farooq F, Vohra H, Fang Q, Liu W, Wattenberg BW, Gong X.
Xie T, et al. Among authors: mahawar u.
Nat Commun. 2023 Jun 13;14(1):3475. doi: 10.1038/s41467-023-39274-y.
Nat Commun. 2023.
PMID: 37308477
Free PMC article.
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CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism.
Green CD, Weigel C, Oyeniran C, James BN, Davis D, Mahawar U, Newton J, Wattenberg BW, Maceyka M, Spiegel S.
Green CD, et al. Among authors: mahawar u.
J Lipid Res. 2021;62:100082. doi: 10.1016/j.jlr.2021.100082. Epub 2021 Apr 30.
J Lipid Res. 2021.
PMID: 33939982
Free PMC article.
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Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination.
Davis DL, Mahawar U, Pope VS, Allegood J, Sato-Bigbee C, Wattenberg BW.
Davis DL, et al. Among authors: mahawar u.
J Lipid Res. 2020 Apr;61(4):505-522. doi: 10.1194/jlr.RA120000627. Epub 2020 Feb 10.
J Lipid Res. 2020.
PMID: 32041816
Free PMC article.
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Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4.
Girdhar A, Bharathi V, Tiwari VR, Abhishek S, Deeksha W, Mahawar US, Raju G, Singh SK, Prabusankar G, Rajakumara E, Patel BK.
Girdhar A, et al. Among authors: mahawar us.
Int J Biol Macromol. 2020 Mar 15;147:117-130. doi: 10.1016/j.ijbiomac.2020.01.032. Epub 2020 Jan 7.
Int J Biol Macromol. 2020.
PMID: 31917988
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