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Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity.
Heindel DW, Koppolu S, Zhang Y, Kasper B, Meche L, Vaiana CA, Bissel SJ, Carter CE, Kelvin AA, Elaish M, Lopez-Orozco J, Zhang B, Zhou B, Chou TW, Lashua L, Hobman TC, Ross TM, Ghedin E, Mahal LK. Heindel DW, et al. Among authors: mahal lk. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26926-26935. doi: 10.1073/pnas.2008203117. Epub 2020 Oct 12. Proc Natl Acad Sci U S A. 2020. PMID: 33046650 Free PMC article.
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Nguyen L, McCord KA, Bui DT, Bouwman KM, Kitova EN, Elaish M, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yang TJ, Willows SD, Mason AL, Mahal LK, Lowary TL, West LJ, Hsu SD, Hobman T, Tompkins SM, Boons GJ, de Vries RP, Macauley MS, Klassen JS. Nguyen L, et al. Among authors: mahal lk. Nat Chem Biol. 2022 Jan;18(1):81-90. doi: 10.1038/s41589-021-00924-1. Epub 2021 Nov 9. Nat Chem Biol. 2022. PMID: 34754101
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N. Xu Z, et al. Among authors: mahal lk. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204539119. doi: 10.1073/pnas.2204539119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878012 Free PMC article.
Absolute Affinities from Quantitative Shotgun Glycomics Using Concentration-Independent (COIN) Native Mass Spectrometry.
Bui DT, Favell J, Kitova EN, Li Z, McCord KA, Schmidt EN, Mozaneh F, Elaish M, El-Hawiet A, St-Pierre Y, Hobman TC, Macauley MS, Mahal LK, Flynn MR, Klassen JS. Bui DT, et al. Among authors: mahal lk. ACS Cent Sci. 2023 Jun 15;9(7):1374-1387. doi: 10.1021/acscentsci.3c00294. eCollection 2023 Jul 26. ACS Cent Sci. 2023. PMID: 37521792 Free PMC article.
α2,6-Sialylation Is Upregulated in Severe COVID-19, Implicating the Complement Cascade.
Qin R, Kurz E, Chen S, Zeck B, Chiribogas L, Jackson D, Herchen A, Attia T, Carlock M, Rapkiewicz A, Bar-Sagi D, Ritchie B, Ross TM, Mahal LK. Qin R, et al. Among authors: mahal lk. ACS Infect Dis. 2022 Nov 11;8(11):2348-2361. doi: 10.1021/acsinfecdis.2c00421. Epub 2022 Oct 11. ACS Infect Dis. 2022. PMID: 36219583 Free PMC article.
Insights into miRNA regulation of the human glycome.
Kasper BT, Koppolu S, Mahal LK. Kasper BT, et al. Among authors: mahal lk. Biochem Biophys Res Commun. 2014 Mar 21;445(4):774-9. doi: 10.1016/j.bbrc.2014.01.034. Epub 2014 Jan 23. Biochem Biophys Res Commun. 2014. PMID: 24463102 Free PMC article.
102 results