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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates.
Brown KM, Nair JK, Janas MM, Anglero-Rodriguez YI, Dang LTH, Peng H, Theile CS, Castellanos-Rizaldos E, Brown C, Foster D, Kurz J, Allen J, Maganti R, Li J, Matsuda S, Stricos M, Chickering T, Jung M, Wassarman K, Rollins J, Woods L, Kelin A, Guenther DC, Mobley MW, Petrulis J, McDougall R, Racie T, Bombardier J, Cha D, Agarwal S, Johnson L, Jiang Y, Lentini S, Gilbert J, Nguyen T, Chigas S, LeBlanc S, Poreci U, Kasper A, Rogers AB, Chong S, Davis W, Sutherland JE, Castoreno A, Milstein S, Schlegel MK, Zlatev I, Charisse K, Keating M, Manoharan M, Fitzgerald K, Wu JT, Maier MA, Jadhav V. Brown KM, et al. Among authors: maganti r. Nat Biotechnol. 2022 Oct;40(10):1500-1508. doi: 10.1038/s41587-022-01334-x. Epub 2022 Jun 2. Nat Biotechnol. 2022. PMID: 35654979
Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
Matsuda S, Bala S, Liao JY, Datta D, Mikami A, Woods L, Harp JM, Gilbert JA, Bisbe A, Manoharan RM, Kim M, Theile CS, Guenther DC, Jiang Y, Agarwal S, Maganti R, Schlegel MK, Zlatev I, Charisse K, Rajeev KG, Castoreno A, Maier M, Janas MM, Egli M, Chaput JC, Manoharan M. Matsuda S, et al. Among authors: maganti r. J Am Chem Soc. 2023 Sep 13;145(36):19691-19706. doi: 10.1021/jacs.3c04744. Epub 2023 Aug 28. J Am Chem Soc. 2023. PMID: 37638886
Multi-shell connectome DWI-based graph theory measures for the prediction of temporal lobe epilepsy and cognition.
Garcia-Ramos C, Adluru N, Chu DY, Nair V, Adluru A, Nencka A, Maganti R, Mathis J, Conant LL, Alexander AL, Prabhakaran V, Binder JR, Meyerand ME, Hermann B, Struck AF. Garcia-Ramos C, et al. Among authors: maganti r. Cereb Cortex. 2023 Jun 8;33(12):8056-8065. doi: 10.1093/cercor/bhad098. Cereb Cortex. 2023. PMID: 37067514 Free PMC article.
Late dominance of the right hemisphere during narrative comprehension.
Youssofzadeh V, Conant L, Stout J, Ustine C, Humphries C, Gross WL, Shah-Basak P, Mathis J, Awe E, Allen L, DeYoe EA, Carlson C, Anderson CT, Maganti R, Hermann B, Nair VA, Prabhakaran V, Meyerand B, Binder JR, Raghavan M. Youssofzadeh V, et al. Among authors: maganti r. Neuroimage. 2022 Dec 1;264:119749. doi: 10.1016/j.neuroimage.2022.119749. Epub 2022 Nov 13. Neuroimage. 2022. PMID: 36379420 Free PMC article.
90 results