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Substance P and Prokineticin-2 are overexpressed in olfactory neurons and play differential roles in persons with persistent post-COVID-19 olfactory dysfunction.
Schirinzi T, Lattanzi R, Maftei D, Grillo P, Zenuni H, Boffa L, Albanese M, Simonetta C, Bovenzi R, Maurizi R, Loccisano L, Vincenzi M, Greco A, Di Girolamo S, Mercuri NB, Passali FM, Severini C. Schirinzi T, et al. Among authors: maftei d. Brain Behav Immun. 2023 Feb;108:302-308. doi: 10.1016/j.bbi.2022.12.017. Epub 2022 Dec 19. Brain Behav Immun. 2023. PMID: 36549578 Free PMC article.
Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals.
Maftei D, Marconi V, Florenzano F, Giancotti LA, Castelli M, Moretti S, Borsani E, Rodella LF, Balboni G, Luongo L, Maione S, Sacerdote P, Negri L, Lattanzi R. Maftei D, et al. Br J Pharmacol. 2014 Nov;171(21):4850-65. doi: 10.1111/bph.12793. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24902717 Free PMC article.
Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model.
Lattanzi R, Maftei D, Marconi V, Florenzano F, Franchi S, Borsani E, Rodella LF, Balboni G, Salvadori S, Sacerdote P, Negri L. Lattanzi R, et al. Among authors: maftei d. Biomed Res Int. 2015;2015:301292. doi: 10.1155/2015/301292. Epub 2015 Jan 5. Biomed Res Int. 2015. PMID: 25685780 Free PMC article.
Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity.
Severini C, Lattanzi R, Maftei D, Marconi V, Ciotti MT, Petrocchi Passeri P, Florenzano F, Del Duca E, Caioli S, Zona C, Balboni G, Salvadori S, Nisticò R, Negri L. Severini C, et al. Among authors: maftei d. Sci Rep. 2015 Oct 19;5:15301. doi: 10.1038/srep15301. Sci Rep. 2015. PMID: 26477583 Free PMC article.
57 results