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The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression.
Maes M, Leonard BE, Myint AM, Kubera M, Verkerk R. Maes M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):702-21. doi: 10.1016/j.pnpbp.2010.12.017. Epub 2010 Dec 23. Prog Neuropsychopharmacol Biol Psychiatry. 2011. PMID: 21185346 Review.
Putative neuroprotective agents in neuropsychiatric disorders.
Dodd S, Maes M, Anderson G, Dean OM, Moylan S, Berk M. Dodd S, et al. Among authors: maes m. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Apr 5;42:135-45. doi: 10.1016/j.pnpbp.2012.11.007. Epub 2012 Nov 23. Prog Neuropsychopharmacol Biol Psychiatry. 2013. PMID: 23178231 Review.
Body image dissatisfaction in pregnant and non-pregnant females is strongly predicted by immune activation and mucosa-derived activation of the tryptophan catabolite (TRYCAT) pathway.
Roomruangwong C, Kanchanatawan B, Carvalho AF, Sirivichayakul S, Duleu S, Geffard M, Maes M. Roomruangwong C, et al. Among authors: maes m. World J Biol Psychiatry. 2018 Apr;19(3):200-209. doi: 10.1080/15622975.2016.1213881. Epub 2016 Aug 30. World J Biol Psychiatry. 2018. PMID: 27427239
1,463 results