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Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.
de Oliveira Rezende Júnior C, Martinez PDG, Ferreira RAA, Koovits PJ, Miranda Soares B, Ferreira LLG, Michelan-Duarte S, Chelucci RC, Andricopulo AD, Matheeussen A, Van Pelt N, Caljon G, Maes L, Campbell S, Kratz JM, Mowbray CE, Dias LC. de Oliveira Rezende Júnior C, et al. Among authors: maes l. Eur J Med Chem. 2023 Jan 15;246:114925. doi: 10.1016/j.ejmech.2022.114925. Epub 2022 Nov 15. Eur J Med Chem. 2023. PMID: 36459758 Free article.
Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites.
Dirkx L, Van Acker SI, Nicolaes Y, Cunha JLR, Ahmad R, Hendrickx R, Caljon B, Imamura H, Ebo DG, Jeffares DC, Sterckx YG, Maes L, Hendrickx S, Caljon G. Dirkx L, et al. Among authors: maes l. PLoS Pathog. 2024 Apr 24;20(4):e1012181. doi: 10.1371/journal.ppat.1012181. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38656959 Free PMC article.
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging.
Trometer N, Pecourneau J, Feng L, Navarro-Huerta JA, Lazarin-Bidóia D, de Oliveira Silva Lautenschlager S, Maes L, Fortes Francisco A, Kelly JM, Meunier B, Cal M, Mäser P, Kaiser M, Davioud-Charvet E. Trometer N, et al. Among authors: maes l. ACS Infect Dis. 2024 May 10;10(5):1808-1838. doi: 10.1021/acsinfecdis.4c00137. Epub 2024 Apr 12. ACS Infect Dis. 2024. PMID: 38606978
Design of HIV-1 protease inhibitors active on multidrug-resistant virus.
Surleraux DL, de Kock HA, Verschueren WG, Pille GM, Maes LJ, Peeters A, Vendeville S, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Surleraux DL, et al. Among authors: maes lj. J Med Chem. 2005 Mar 24;48(6):1965-73. doi: 10.1021/jm049454n. J Med Chem. 2005. PMID: 15771440
Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones.
Gendron T, Lanfranchi DA, Wenzel NI, Kessedjian H, Jannack B, Maes L, Cojean S, Müller TJJ, Loiseau PM, Davioud-Charvet E. Gendron T, et al. Among authors: maes l. Molecules. 2024 Apr 4;29(7):1620. doi: 10.3390/molecules29071620. Molecules. 2024. PMID: 38611899 Free PMC article.
808 results