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A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization.
Hashimoto Y, Koyama K, Kamai Y, Hirotani K, Ogitani Y, Zembutsu A, Abe M, Kaneda Y, Maeda N, Shiose Y, Iguchi T, Ishizaka T, Karibe T, Hayakawa I, Morita K, Nakada T, Nomura T, Wakita K, Kagari T, Abe Y, Murakami M, Ueno S, Agatsuma T. Hashimoto Y, et al. Among authors: maeda n. Clin Cancer Res. 2019 Dec 1;25(23):7151-7161. doi: 10.1158/1078-0432.CCR-19-1745. Epub 2019 Aug 30. Clin Cancer Res. 2019. PMID: 31471314
U3-1402 sensitizes HER3-expressing tumors to PD-1 blockade by immune activation.
Haratani K, Yonesaka K, Takamura S, Maenishi O, Kato R, Takegawa N, Kawakami H, Tanaka K, Hayashi H, Takeda M, Maeda N, Kagari T, Hirotani K, Tsurutani J, Nishio K, Doi K, Miyazawa M, Nakagawa K. Haratani K, et al. Among authors: maeda n. J Clin Invest. 2020 Jan 2;130(1):374-388. doi: 10.1172/JCI126598. J Clin Invest. 2020. PMID: 31661465 Free PMC article.
Pan-cancer gene expression analysis of tissue microarray using EdgeSeq oncology biomarker panel and a cross-comparison with HER2 and HER3 immunohistochemical analysis.
Inaki K, Shibutani T, Maeda N, Eppenberger-Castori S, Nicolet S, Kaneda Y, Koyama K, Qiu Y, Wakita K, Murakami M. Inaki K, et al. Among authors: maeda n. PLoS One. 2022 Sep 22;17(9):e0274140. doi: 10.1371/journal.pone.0274140. eCollection 2022. PLoS One. 2022. PMID: 36137139 Free PMC article.
ACAT inhibitor pactimibe sulfate (CS-505) reduces and stabilizes atherosclerotic lesions by cholesterol-lowering and direct effects in apolipoprotein E-deficient mice.
Terasaka N, Miyazaki A, Kasanuki N, Ito K, Ubukata N, Koieyama T, Kitayama K, Tanimoto T, Maeda N, Inaba T. Terasaka N, et al. Among authors: maeda n. Atherosclerosis. 2007 Feb;190(2):239-47. doi: 10.1016/j.atherosclerosis.2006.03.007. Epub 2006 Apr 19. Atherosclerosis. 2007. PMID: 16626720
DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model.
Jimbo T, Hatanaka M, Komatsu T, Taira T, Kumazawa K, Maeda N, Suzuki T, Ota M, Haginoya N, Isoyama T, Fujiwara K. Jimbo T, et al. Among authors: maeda n. Oncotarget. 2019 Aug 27;10(50):5152-5167. doi: 10.18632/oncotarget.27114. eCollection 2019 Aug 27. Oncotarget. 2019. PMID: 31497246 Free PMC article.
2,160 results