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Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.
Koyani CN, Kolesnik E, Wölkart G, Shrestha N, Scheruebel S, Trummer C, Zorn-Pauly K, Hammer A, Lang P, Reicher H, Maechler H, Groschner K, Mayer B, Rainer PP, Sourij H, Sattler W, Malle E, Pelzmann B, von Lewinski D. Koyani CN, et al. Among authors: maechler h. Biochem Pharmacol. 2017 Dec 1;145:64-80. doi: 10.1016/j.bcp.2017.08.021. Epub 2017 Aug 30. Biochem Pharmacol. 2017. PMID: 28859968 Free article.
Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes.
Rainer PP, Doleschal B, Kirk JA, Sivakumaran V, Saad Z, Groschner K, Maechler H, Hoefler G, Bauernhofer T, Samonigg H, Hutterer G, Kass DA, Pieske B, von Lewinski D, Pichler M. Rainer PP, et al. Among authors: maechler h. BJU Int. 2012 Nov;110(10):1455-62. doi: 10.1111/j.1464-410X.2012.11134.x. Epub 2012 Apr 17. BJU Int. 2012. PMID: 22508007
miR-1183 Is a Key Marker of Remodeling upon Stretch and Tachycardia in Human Myocardium.
Djalinac N, Kolesnik E, Maechler H, Scheruebel-Posch S, Pelzmann B, Rainer PP, Foessl I, Wallner M, Scherr D, Heinemann A, Sedej S, Ljubojevic-Holzer S, von Lewinski D, Bisping E. Djalinac N, et al. Among authors: maechler h. Int J Mol Sci. 2022 Jun 23;23(13):6962. doi: 10.3390/ijms23136962. Int J Mol Sci. 2022. PMID: 35805966 Free PMC article.
HDAC Inhibition Regulates Cardiac Function by Increasing Myofilament Calcium Sensitivity and Decreasing Diastolic Tension.
Eaton DM, Martin TG, Kasa M, Djalinac N, Ljubojevic-Holzer S, Von Lewinski D, Pöttler M, Kampaengsri T, Krumphuber A, Scharer K, Maechler H, Zirlik A, McKinsey TA, Kirk JA, Houser SR, Rainer PP, Wallner M. Eaton DM, et al. Among authors: maechler h. Pharmaceutics. 2022 Jul 21;14(7):1509. doi: 10.3390/pharmaceutics14071509. Pharmaceutics. 2022. PMID: 35890404 Free PMC article.
Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node.
Shrestha N, Zorn-Pauly K, Mesirca P, Koyani CN, Wölkart G, Di Biase V, Torre E, Lang P, Gorischek A, Schreibmayer W, Arnold R, Maechler H, Mayer B, von Lewinski D, Torrente AG, Mangoni ME, Pelzmann B, Scheruebel S. Shrestha N, et al. Among authors: maechler h. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2210152120. doi: 10.1073/pnas.2210152120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406102 Free PMC article.
A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction.
Schwarzl M, Hamdani N, Seiler S, Alogna A, Manninger M, Reilly S, Zirngast B, Kirsch A, Steendijk P, Verderber J, Zweiker D, Eller P, Höfler G, Schauer S, Eller K, Maechler H, Pieske BM, Linke WA, Casadei B, Post H. Schwarzl M, et al. Among authors: maechler h. Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1407-18. doi: 10.1152/ajpheart.00542.2015. Epub 2015 Sep 4. Am J Physiol Heart Circ Physiol. 2015. PMID: 26342070 Free article.
21 results