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Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?
Griffiths K, Ida T, Morita M, Lamb RJ, Lee JJ, Frenneaux MP, Fukuto JM, Akaike T, Feelisch M, Madhani M. Griffiths K, et al. Among authors: madhani m. Redox Biol. 2023 Apr;60:102605. doi: 10.1016/j.redox.2023.102605. Epub 2023 Jan 10. Redox Biol. 2023. PMID: 36657187 Free PMC article.
Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.
Feelisch M, Akaike T, Griffiths K, Ida T, Prysyazhna O, Goodwin JJ, Gollop ND, Fernandez BO, Minnion M, Cortese-Krott MM, Borgognone A, Hayes RM, Eaton P, Frenneaux MP, Madhani M. Feelisch M, et al. Among authors: madhani m. Cardiovasc Res. 2020 Jan 1;116(1):51-62. doi: 10.1093/cvr/cvz202. Cardiovasc Res. 2020. PMID: 31372656 Free PMC article.
Cardiac metabolism - A promising therapeutic target for heart failure.
Noordali H, Loudon BL, Frenneaux MP, Madhani M. Noordali H, et al. Among authors: madhani m. Pharmacol Ther. 2018 Feb;182:95-114. doi: 10.1016/j.pharmthera.2017.08.001. Epub 2017 Aug 15. Pharmacol Ther. 2018. PMID: 28821397 Free article. Review.
Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite.
Maher AR, Arif S, Madhani M, Abozguia K, Ahmed I, Fernandez BO, Feelisch M, O'Sullivan AG, Christopoulos A, Sverdlov AL, Ngo D, Dautov R, James PE, Horowitz JD, Frenneaux MP. Maher AR, et al. Among authors: madhani m. Br J Pharmacol. 2013 Jun;169(3):659-70. doi: 10.1111/bph.12152. Br J Pharmacol. 2013. PMID: 23472879 Free PMC article. Clinical Trial.
Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans.
Arif S, Borgognone A, Lin EL, O'Sullivan AG, Sharma V, Drury NE, Menon A, Nightingale P, Mascaro J, Bonser RS, Horowitz JD, Feelisch M, Frenneaux MP, Madhani M. Arif S, et al. Among authors: madhani m. Br J Pharmacol. 2015 Jul;172(13):3341-52. doi: 10.1111/bph.13122. Epub 2015 Apr 29. Br J Pharmacol. 2015. PMID: 25754766 Free PMC article.
43 results