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PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Deschoemaeker S, Di Conza G, Lilla S, Martín-Pérez R, Mennerich D, Boon L, Hendrikx S, Maddocks OD, Marx C, Radhakrishnan P, Prenen H, Schneider M, Myllyharju J, Kietzmann T, Vousden KH, Zanivan S, Mazzone M. Deschoemaeker S, et al. Among authors: maddocks od. EMBO Mol Med. 2015 Oct;7(10):1350-65. doi: 10.15252/emmm.201505492. EMBO Mol Med. 2015. PMID: 26290450 Free PMC article.
Autophagy promotes cell survival by maintaining NAD levels.
Kataura T, Sedlackova L, Otten EG, Kumari R, Shapira D, Scialo F, Stefanatos R, Ishikawa KI, Kelly G, Seranova E, Sun C, Maetzel D, Kenneth N, Trushin S, Zhang T, Trushina E, Bascom CC, Tasseff R, Isfort RJ, Oblong JE, Miwa S, Lazarou M, Jaenisch R, Imoto M, Saiki S, Papamichos-Chronakis M, Manjithaya R, Maddocks ODK, Sanz A, Sarkar S, Korolchuk VI. Kataura T, et al. Among authors: maddocks odk. Dev Cell. 2022 Nov 21;57(22):2584-2598.e11. doi: 10.1016/j.devcel.2022.10.008. Dev Cell. 2022. PMID: 36413951 Free article.
Metabolic regulation by p53.
Maddocks OD, Vousden KH. Maddocks OD, et al. J Mol Med (Berl). 2011 Mar;89(3):237-45. doi: 10.1007/s00109-011-0735-5. Epub 2011 Feb 23. J Mol Med (Berl). 2011. PMID: 21340684 Free PMC article. Review.
Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Chaneton B, Hillmann P, Zheng L, Martin ACL, Maddocks ODK, Chokkathukalam A, Coyle JE, Jankevics A, Holding FP, Vousden KH, Frezza C, O'Reilly M, Gottlieb E. Chaneton B, et al. Nature. 2012 Nov 15;491(7424):458-462. doi: 10.1038/nature11540. Epub 2012 Oct 14. Nature. 2012. PMID: 23064226 Free PMC article.
Metabolic regulation by p53 family members.
Berkers CR, Maddocks OD, Cheung EC, Mor I, Vousden KH. Berkers CR, et al. Among authors: maddocks od. Cell Metab. 2013 Nov 5;18(5):617-33. doi: 10.1016/j.cmet.2013.06.019. Epub 2013 Aug 15. Cell Metab. 2013. PMID: 23954639 Free PMC article. Review.
47 results