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SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways.
Majeed Y, Halabi N, Madani AY, Engelke R, Bhagwat AM, Abdesselem H, Agha MV, Vakayil M, Courjaret R, Goswami N, Hamidane HB, Elrayess MA, Rafii A, Graumann J, Schmidt F, Mazloum NA. Majeed Y, et al. Among authors: madani ay. Sci Rep. 2021 Apr 14;11(1):8177. doi: 10.1038/s41598-021-87759-x. Sci Rep. 2021. PMID: 33854178 Free PMC article.
SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition.
Abdesselem H, Madani A, Hani A, Al-Noubi M, Goswami N, Ben Hamidane H, Billing AM, Pasquier J, Bonkowski MS, Halabi N, Dalloul R, Sheriff MZ, Mesaeli N, ElRayess M, Sinclair DA, Graumann J, Mazloum NA. Abdesselem H, et al. J Biol Chem. 2016 Jan 29;291(5):2119-35. doi: 10.1074/jbc.M115.675645. Epub 2015 Dec 11. J Biol Chem. 2016. PMID: 26655722 Free PMC article.