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Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function.
J Med Chem. 2011 Mar 24;54(6):1667-81. doi: 10.1021/jm1012903. Epub 2011 Feb 22.
J Med Chem. 2011.
PMID: 21341682
Free PMC article.
Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators.
Lum RT, Cheng M, Cristobal CP, Goldfine ID, Evans JL, Keck JG, Macsata RW, Manchem VP, Matsumoto Y, Park SJ, Rao SS, Robinson L, Shi S, Spevak WR, Schow SR.
Lum RT, et al. Among authors: macsata rw.
J Med Chem. 2008 Oct 9;51(19):6173-87. doi: 10.1021/jm800600v. Epub 2008 Sep 13.
J Med Chem. 2008.
PMID: 18788731
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5-Substituted isophthalamides as insulin receptor sensitizers.
Robinson L, Bajjalieh S, Cairns N, Lum RT, Macsata RW, Manchem VP, Park SJ, Rao S, Schow SR, Shi S, Spevak WR.
Robinson L, et al. Among authors: macsata rw.
Bioorg Med Chem Lett. 2008 Jun 15;18(12):3492-4. doi: 10.1016/j.bmcl.2008.05.031. Epub 2008 May 15.
Bioorg Med Chem Lett. 2008.
PMID: 18513965
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In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.
Cheng M, Chen S, Schow SR, Manchem VP, Spevak WR, Cristobal CP, Shi S, Macsata RW, Lum RT, Goldfine ID, Keck JG.
Cheng M, et al. Among authors: macsata rw.
J Cell Biochem. 2004 Aug 15;92(6):1234-45. doi: 10.1002/jcb.20150.
J Cell Biochem. 2004.
PMID: 15258906
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p-Nitrobenzyl side-chain protection for solid-phase synthesis.
Hocker MD, Caldwell CG, Macsata RW, Lyttle MH.
Hocker MD, et al. Among authors: macsata rw.
Pept Res. 1995 Nov-Dec;8(6):310-15.
Pept Res. 1995.
PMID: 8838413
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