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Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations.
Nat Commun. 2022 Dec 22;13(1):7886. doi: 10.1038/s41467-022-35639-x.
Nat Commun. 2022.
PMID: 36550158
Free PMC article.
The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies.
Vignier N, Chatzifrangkeskou M, Pinton L, Wioland H, Marais T, Lemaitre M, Le Dour C, Peccate C, Cardoso D, Schmitt A, Wu W, Biferi MG, Naouar N, Macquart C, Beuvin M, Decostre V, Bonne G, Romet-Lemonne G, Worman HJ, Tedesco FS, Jégou A, Muchir A.
Vignier N, et al. Among authors: macquart c.
Cell Rep. 2021 Aug 24;36(8):109601. doi: 10.1016/j.celrep.2021.109601.
Cell Rep. 2021.
PMID: 34433058
Free PMC article.
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Microtubule cytoskeleton regulates Connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene.
Macquart C, Jüttner R, Morales Rodriguez B, Le Dour C, Lefebvre F, Chatzifrangkeskou M, Schmitt A, Gotthardt M, Bonne G, Muchir A.
Macquart C, et al.
Hum Mol Genet. 2019 Dec 15;28(24):4043-4052. doi: 10.1093/hmg/ddy227.
Hum Mol Genet. 2019.
PMID: 29893868
Free article.
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Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation.
Chatzifrangkeskou M, Yadin D, Marais T, Chardonnet S, Cohen-Tannoudji M, Mougenot N, Schmitt A, Crasto S, Di Pasquale E, Macquart C, Tanguy Y, Jebeniani I, Pucéat M, Morales Rodriguez B, Goldmann WH, Dal Ferro M, Biferi MG, Knaus P, Bonne G, Worman HJ, Muchir A.
Chatzifrangkeskou M, et al. Among authors: macquart c.
Hum Mol Genet. 2018 Sep 1;27(17):3060-3078. doi: 10.1093/hmg/ddy215.
Hum Mol Genet. 2018.
PMID: 29878125
Free PMC article.
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Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene.
Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow JP, Worman HJ, Muchir A.
Le Dour C, et al. Among authors: macquart c.
Hum Mol Genet. 2017 Jan 15;26(2):333-343. doi: 10.1093/hmg/ddw389.
Hum Mol Genet. 2017.
PMID: 28069793
Free PMC article.
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