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Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling.
Zindel J, Mittner J, Bayer J, April-Monn SL, Kohler A, Nusse Y, Dosch M, Büchi I, Sanchez-Taltavull D, Dawson H, Gomez de Agüero M, Asahina K, Kubes P, Macpherson AJ, Stroka D, Candinas D. Zindel J, et al. Among authors: macpherson aj. Nat Commun. 2021 Dec 16;12(1):7316. doi: 10.1038/s41467-021-27612-x. Nat Commun. 2021. PMID: 34916513 Free PMC article.
Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response.
Uchimura Y, Fuhrer T, Li H, Lawson MA, Zimmermann M, Yilmaz B, Zindel J, Ronchi F, Sorribas M, Hapfelmeier S, Ganal-Vonarburg SC, Gomez de Agüero M, McCoy KD, Sauer U, Macpherson AJ. Uchimura Y, et al. Among authors: macpherson aj. Immunity. 2018 Sep 18;49(3):545-559.e5. doi: 10.1016/j.immuni.2018.08.004. Epub 2018 Sep 4. Immunity. 2018. PMID: 30193848 Free PMC article.
The maternal microbiota drives early postnatal innate immune development.
Gomez de Agüero M, Ganal-Vonarburg SC, Fuhrer T, Rupp S, Uchimura Y, Li H, Steinert A, Heikenwalder M, Hapfelmeier S, Sauer U, McCoy KD, Macpherson AJ. Gomez de Agüero M, et al. Among authors: macpherson aj. Science. 2016 Mar 18;351(6279):1296-302. doi: 10.1126/science.aad2571. Science. 2016. PMID: 26989247
The immunological functions of the Appendix: An example of redundancy?
Girard-Madoux MJH, Gomez de Agüero M, Ganal-Vonarburg SC, Mooser C, Belz GT, Macpherson AJ, Vivier E. Girard-Madoux MJH, et al. Among authors: macpherson aj. Semin Immunol. 2018 Apr;36:31-44. doi: 10.1016/j.smim.2018.02.005. Epub 2018 Mar 2. Semin Immunol. 2018. PMID: 29503124 Review.
Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice.
Yilmaz B, Mooser C, Keller I, Li H, Zimmermann J, Bosshard L, Fuhrer T, Gomez de Agüero M, Trigo NF, Tschanz-Lischer H, Limenitakis JP, Hardt WD, McCoy KD, Stecher B, Excoffier L, Sauer U, Ganal-Vonarburg SC, Macpherson AJ. Yilmaz B, et al. Among authors: macpherson aj. Cell Host Microbe. 2021 Apr 14;29(4):650-663.e9. doi: 10.1016/j.chom.2021.02.001. Epub 2021 Mar 3. Cell Host Microbe. 2021. PMID: 33662276 Free article.
MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice.
Healy ME, Boege Y, Hodder MC, Böhm F, Malehmir M, Scherr AL, Jetzer J, Chan LK, Parrotta R, Jacobs K, Clerbaux LA, Kreutzer S, Campbell A, Gilchrist E, Gilroy K, Rodewald AK, Honcharova-Biletska H, Schimmer R, Vélez K, Büeler S, Cammareri P, Kalna G, Wenning AS, McCoy KD, Gomez de Agüero M, Schulze-Bergkamen H, Klose CSN, Unger K, Macpherson AJ, Moor AE, Köhler B, Sansom OJ, Heikenwälder M, Weber A. Healy ME, et al. Among authors: macpherson aj. Gastroenterology. 2020 Jul;159(1):183-199. doi: 10.1053/j.gastro.2020.03.017. Epub 2020 Mar 14. Gastroenterology. 2020. PMID: 32179094 Free PMC article.
The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota.
Balmer ML, Slack E, de Gottardi A, Lawson MA, Hapfelmeier S, Miele L, Grieco A, Van Vlierberghe H, Fahrner R, Patuto N, Bernsmeier C, Ronchi F, Wyss M, Stroka D, Dickgreber N, Heim MH, McCoy KD, Macpherson AJ. Balmer ML, et al. Among authors: macpherson aj. Sci Transl Med. 2014 May 21;6(237):237ra66. doi: 10.1126/scitranslmed.3008618. Sci Transl Med. 2014. PMID: 24848256 Free article.
247 results