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CD4 T cells are required for both development and maintenance of disease in a new mouse model of reversible colitis.
Brasseit J, Althaus-Steiner E, Faderl M, Dickgreber N, Saurer L, Genitsch V, Dolowschiak T, Li H, Finke D, Hardt WD, McCoy KD, Macpherson AJ, Corazza N, Noti M, Mueller C. Brasseit J, et al. Among authors: macpherson aj. Mucosal Immunol. 2016 May;9(3):689-701. doi: 10.1038/mi.2015.93. Epub 2015 Sep 16. Mucosal Immunol. 2016. PMID: 26376366 Free article.
The maternal microbiota drives early postnatal innate immune development.
Gomez de Agüero M, Ganal-Vonarburg SC, Fuhrer T, Rupp S, Uchimura Y, Li H, Steinert A, Heikenwalder M, Hapfelmeier S, Sauer U, McCoy KD, Macpherson AJ. Gomez de Agüero M, et al. Among authors: macpherson aj. Science. 2016 Mar 18;351(6279):1296-302. doi: 10.1126/science.aad2571. Science. 2016. PMID: 26989247
Publisher Correction: Microbial network disturbances in relapsing refractory Crohn's disease.
Yilmaz B, Juillerat P, Øyås O, Ramon C, Bravo FD, Franc Y, Fournier N, Michetti P, Mueller C, Geuking M, Pittet VEH, Maillard MH, Rogler G; Swiss IBD Cohort Investigators; Wiest R, Stelling J, Macpherson AJ. Yilmaz B, et al. Among authors: macpherson aj. Nat Med. 2019 Apr;25(4):701. doi: 10.1038/s41591-019-0411-9. Nat Med. 2019. PMID: 30846883
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease.
Serra EG, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, Kammermeier J, Croft NM, Posovszky C, Rodrigues A, Russell RK, Barakat F, Auth MKH, Heuschkel R, Zilbauer M, Fyderek K, Braegger C, Travis SP, Satsangi J, Parkes M, Thapar N, Ferry H, Matte JC, Gilmour KC, Wedrychowicz A, Sullivan P, Moore C, Sambrook J, Ouwehand W, Roberts D, Danesh J, Baeumler TA, Fulga TA, Carrami EM, Ahmed A, Wilson R, Barrett JC, Elkadri A, Griffiths AM; COLORS in IBD group investigators; Oxford IBD cohort study investigators; INTERVAL Study; Swiss IBD cohort investigators; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium; Snapper SB, Shah N, Muise AM, Wilson DC, Uhlig HH, Anderson CA. Serra EG, et al. Nat Commun. 2020 Feb 21;11(1):995. doi: 10.1038/s41467-019-14275-y. Nat Commun. 2020. PMID: 32081864 Free PMC article.
247 results