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The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy.
Oncogene. 2020 Oct;39(41):6421-6436. doi: 10.1038/s41388-020-01436-3. Epub 2020 Aug 31.
Oncogene. 2020.
PMID: 32868877
Free PMC article.
TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer.
Varela FA, Foust VL, Hyland TE, Sala-Hamrick KE, Mackinder JR, Martin CE, Murray AS, Todi SV, List K.
Varela FA, et al. Among authors: mackinder jr.
Sci Rep. 2020 Aug 17;10(1):13896. doi: 10.1038/s41598-020-70636-4.
Sci Rep. 2020.
PMID: 32807808
Free PMC article.
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Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization.
Martin CE, Murray AS, Sala-Hamrick KE, Mackinder JR, Harrison EC, Lundgren JG, Varela FA, List K.
Martin CE, et al. Among authors: mackinder jr.
J Biol Chem. 2021 Oct;297(4):101227. doi: 10.1016/j.jbc.2021.101227. Epub 2021 Sep 22.
J Biol Chem. 2021.
PMID: 34562451
Free PMC article.
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TMPRSS13 zymogen activation, surface localization, and shedding is regulated by proteolytic cleavage within the non-catalytic stem region.
Martin CE, Murray AS, Mackinder JR, Sala-Hamrick KE, Flynn MG, Lundgren JG, Varela FA, List K.
Martin CE, et al. Among authors: mackinder jr.
Biol Chem. 2022 Jul 8;403(10):969-982. doi: 10.1515/hsz-2022-0129. Print 2022 Sep 27.
Biol Chem. 2022.
PMID: 35796294
Free PMC article.
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Sphingosine induction of the Pseudomonas aeruginosa hemolytic phospholipase C/sphingomyelinase (PlcH).
Mackinder JR, Hinkel LA, Schutz K, Eckstrom K, Fisher K, Wargo MJ.
Mackinder JR, et al.
J Bacteriol. 2024 Mar 21;206(3):e0038223. doi: 10.1128/jb.00382-23. Epub 2024 Feb 27.
J Bacteriol. 2024.
PMID: 38411048
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