Mackay SP - Search Results

1

Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT.

Clark RL, Clements CJ, Barrett MP, Mackay SP, Rathnam RP, Owusu-Dapaah G, Spencer J, Huggan JK. Clark RL, et al. Among authors: mackay sp. Bioorg Med Chem. 2012 Oct 15;20(20):6019-33. doi: 10.1016/j.bmc.2012.08.049. Epub 2012 Aug 31. Bioorg Med Chem. 2012. PMID: 22985960

2

Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity.

Spencer J, Rathnam RP, Harvey AL, Clements CJ, Clark RL, Barrett MP, Wong PE, Male L, Coles SJ, Mackay SP. Spencer J, et al. Among authors: mackay sp. Bioorg Med Chem. 2011 Mar 1;19(5):1802-15. doi: 10.1016/j.bmc.2011.01.010. Epub 2011 Jan 14. Bioorg Med Chem. 2011. PMID: 21306904

3

Identification of the benzodiazepines as a new class of antileishmanial agent.

Clark RL, Carter KC, Mullen AB, Coxon GD, Owusu-Dapaah G, McFarlane E, Duong Thi MD, Grant MH, Tettey JN, Mackay SP. Clark RL, et al. Among authors: mackay sp. Bioorg Med Chem Lett. 2007 Feb 1;17(3):624-7. doi: 10.1016/j.bmcl.2006.11.004. Epub 2006 Nov 6. Bioorg Med Chem Lett. 2007. PMID: 17113290

4

Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers.

Anthony NG, Baiget J, Berretta G, Boyd M, Breen D, Edwards J, Gamble C, Gray AI, Harvey AL, Hatziieremia S, Ho KH, Huggan JK, Lang S, Llona-Minguez S, Luo JL, McIntosh K, Paul A, Plevin RJ, Robertson MN, Scott R, Suckling CJ, Sutcliffe OB, Young LC, Mackay SP. Anthony NG, et al. Among authors: mackay sp. J Med Chem. 2017 Aug 24;60(16):7043-7066. doi: 10.1021/acs.jmedchem.7b00484. Epub 2017 Aug 15. J Med Chem. 2017. PMID: 28737909 Free PMC article.

5

A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11.

Clark RL, Johnston BF, Suckling CJ, Mackay SP. Clark RL, et al. Among authors: mackay sp. Bioorg Med Chem. 2006 Apr 15;14(8):2674-83. doi: 10.1016/j.bmc.2005.11.042. Epub 2005 Dec 27. Bioorg Med Chem. 2006. PMID: 16378728

6

Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics.

Clark RL, Deane FM, Anthony NG, Johnston BF, McCarthy FO, Mackay SP. Clark RL, et al. Among authors: mackay sp. Bioorg Med Chem. 2007 Jul 15;15(14):4741-52. doi: 10.1016/j.bmc.2007.05.002. Epub 2007 May 6. Bioorg Med Chem. 2007. PMID: 17517513

7

Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages.

Thi MD, Grant MH, Mullen AB, Tettey JN, MacKay SP, Clark RL. Thi MD, et al. Among authors: mackay sp. J Pharm Pharmacol. 2009 Mar;61(3):399-406. doi: 10.1211/jpp/61.03.0017. J Pharm Pharmacol. 2009. PMID: 19222915

8

Current strategies for drug discovery through natural products.

Harvey AL, Clark RL, Mackay SP, Johnston BF. Harvey AL, et al. Among authors: mackay sp. Expert Opin Drug Discov. 2010 Jun;5(6):559-68. doi: 10.1517/17460441.2010.488263. Epub 2010 May 6. Expert Opin Drug Discov. 2010. PMID: 22823167

9

The Drug Discovery Portal: a resource to enhance drug discovery from academia.

Clark RL, Johnston BF, Mackay SP, Breslin CJ, Robertson MN, Harvey AL. Clark RL, et al. Among authors: mackay sp. Drug Discov Today. 2010 Aug;15(15-16):679-83. doi: 10.1016/j.drudis.2010.06.003. Epub 2010 Jun 12. Drug Discov Today. 2010. PMID: 20547242 Review.

10

The drug discovery portal: a computational platform for identifying drug leads from academia.

Clark RL, Johnston BF, Mackay SP, Breslin CJ, Robertson MN, Sutcliffe OB, Dufton MJ, Harvey AL. Clark RL, et al. Among authors: mackay sp. Curr Pharm Des. 2010 May;16(15):1697-702. doi: 10.2174/138161210791164018. Curr Pharm Des. 2010. PMID: 20222856

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

63 results

Search Page