Mackay RI - Search Results

1

A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci.

Ingram SP, Warmenhoven JW, Henthorn NT, Chadiwck AL, Santina EE, McMahon SJ, Schuemann J, Kirkby NF, Mackay RI, Kirkby KJ, Merchant MJ. Ingram SP, et al. Among authors: mackay ri. Commun Biol. 2022 Jul 14;5(1):700. doi: 10.1038/s42003-022-03585-5. Commun Biol. 2022. PMID: 35835982 Free PMC article.

2

Nanodosimetric Simulation of Direct Ion-Induced DNA Damage Using Different Chromatin Geometry Models.

Henthorn NT, Warmenhoven JW, Sotiropoulos M, Mackay RI, Kirkby KJ, Merchant MJ. Henthorn NT, et al. Among authors: mackay ri. Radiat Res. 2017 Dec;188(6):690-703. doi: 10.1667/RR14755.1. Epub 2017 Aug 9. Radiat Res. 2017. PMID: 28792846

3

Modelling direct DNA damage for gold nanoparticle enhanced proton therapy.

Sotiropoulos M, Henthorn NT, Warmenhoven JW, Mackay RI, Kirkby KJ, Merchant MJ. Sotiropoulos M, et al. Among authors: mackay ri. Nanoscale. 2017 Nov 30;9(46):18413-18422. doi: 10.1039/c7nr07310k. Nanoscale. 2017. PMID: 29148554

4

Abstract ID: 171 A Monte Carlo study to reduce range uncertainty in proton beam therapy via prompt gamma-ray detection.

Panaino C, Taylor MJ, MacKay R, Merchant MJ, Price T, Pheonix B, Green S. Panaino C, et al. Phys Med. 2018 Jan;45 Suppl 1:S2. doi: 10.1016/j.ejmp.2017.11.027. Phys Med. 2018. PMID: 29413850

5

In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density.

Henthorn NT, Warmenhoven JW, Sotiropoulos M, Mackay RI, Kirkby NF, Kirkby KJ, Merchant MJ. Henthorn NT, et al. Among authors: mackay ri. Sci Rep. 2018 Feb 8;8(1):2654. doi: 10.1038/s41598-018-21111-8. Sci Rep. 2018. PMID: 29422642 Free PMC article.

6

Proton Beam Therapy - the Challenges of Delivering High-quality Evidence of Clinical Benefit.

National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group (CTRad) Proton Beam Clinical Trial Strategy Group. National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group (CTRad) Proton Beam Clinical Trial Strategy Group. Clin Oncol (R Coll Radiol). 2018 May;30(5):280-284. doi: 10.1016/j.clon.2018.02.031. Epub 2018 Mar 16. Clin Oncol (R Coll Radiol). 2018. PMID: 29551566

7

Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway.

Ingram SP, Warmenhoven JW, Henthorn NT, Smith EAK, Chadwick AL, Burnet NG, Mackay RI, Kirkby NF, Kirkby KJ, Merchant MJ. Ingram SP, et al. Among authors: mackay ri. Sci Rep. 2019 Apr 23;9(1):6359. doi: 10.1038/s41598-019-42901-8. Sci Rep. 2019. PMID: 31015540 Free PMC article.

8

Assessing localized dosimetric effects due to unplanned gas cavities during pelvic MR-guided radiotherapy using Monte Carlo simulations.

Shortall J, Vasquez Osorio E, Chuter R, McWilliam A, Choudhury A, Kirkby K, Mackay R, van Herk M. Shortall J, et al. Med Phys. 2019 Dec;46(12):5807-5815. doi: 10.1002/mp.13857. Epub 2019 Oct 29. Med Phys. 2019. PMID: 31600837

9

Insights into the non-homologous end joining pathway and double strand break end mobility provided by mechanistic in silico modelling.

Warmenhoven JW, Henthorn NT, Ingram SP, Chadwick AL, Sotiropoulos M, Korabel N, Fedotov S, Mackay RI, Kirkby KJ, Merchant MJ. Warmenhoven JW, et al. Among authors: mackay ri. DNA Repair (Amst). 2020 Jan;85:102743. doi: 10.1016/j.dnarep.2019.102743. Epub 2019 Nov 20. DNA Repair (Amst). 2020. PMID: 31759308 Free article.

10

A New Method to Reconstruct in 3D the Emission Position of the Prompt Gamma Rays following Proton Beam Irradiation.

Panaino CMV, Mackay RI, Kirkby KJ, Taylor MJ. Panaino CMV, et al. Among authors: mackay ri. Sci Rep. 2019 Dec 11;9(1):18820. doi: 10.1038/s41598-019-55349-7. Sci Rep. 2019. PMID: 31827167 Free PMC article.

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