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A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus.
Perriman L, Tavakolinia N, Jalali S, Li S, Hickey PF, Amann-Zalcenstein D, Ho WWH, Baldwin TM, Piers AT, Konstantinov IE, Anderson J, Stanley EG, Licciardi PV, Kannourakis G, Naik SH, Koay HF, Mackay LK, Berzins SP, Pellicci DG. Perriman L, et al. Among authors: mackay lk. Sci Immunol. 2023 Jul 21;8(85):eabo4365. doi: 10.1126/sciimmunol.abo4365. Epub 2023 Jul 14. Sci Immunol. 2023. PMID: 37450574
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.
Mackay LK, Rahimpour A, Ma JZ, Collins N, Stock AT, Hafon ML, Vega-Ramos J, Lauzurica P, Mueller SN, Stefanovic T, Tscharke DC, Heath WR, Inouye M, Carbone FR, Gebhardt T. Mackay LK, et al. Nat Immunol. 2013 Dec;14(12):1294-301. doi: 10.1038/ni.2744. Epub 2013 Oct 27. Nat Immunol. 2013. PMID: 24162776
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Mackay LK, Minnich M, Kragten NA, Liao Y, Nota B, Seillet C, Zaid A, Man K, Preston S, Freestone D, Braun A, Wynne-Jones E, Behr FM, Stark R, Pellicci DG, Godfrey DI, Belz GT, Pellegrini M, Gebhardt T, Busslinger M, Shi W, Carbone FR, van Lier RA, Kallies A, van Gisbergen KP. Mackay LK, et al. Science. 2016 Apr 22;352(6284):459-63. doi: 10.1126/science.aad2035. Science. 2016. PMID: 27102484
A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.
Koay HF, Gherardin NA, Enders A, Loh L, Mackay LK, Almeida CF, Russ BE, Nold-Petry CA, Nold MF, Bedoui S, Chen Z, Corbett AJ, Eckle SB, Meehan B, d'Udekem Y, Konstantinov IE, Lappas M, Liu L, Goodnow CC, Fairlie DP, Rossjohn J, Chong MM, Kedzierska K, Berzins SP, Belz GT, McCluskey J, Uldrich AP, Godfrey DI, Pellicci DG. Koay HF, et al. Among authors: mackay lk. Nat Immunol. 2016 Nov;17(11):1300-1311. doi: 10.1038/ni.3565. Epub 2016 Sep 26. Nat Immunol. 2016. PMID: 27668799
TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.
Mielke LA, Liao Y, Clemens EB, Firth MA, Duckworth B, Huang Q, Almeida FF, Chopin M, Koay HF, Bell CA, Hediyeh-Zadeh S, Park SL, Raghu D, Choi J, Putoczki TL, Hodgkin PD, Franks AE, Mackay LK, Godfrey DI, Davis MJ, Xue HH, Bryant VL, Kedzierska K, Shi W, Belz GT. Mielke LA, et al. Among authors: mackay lk. J Exp Med. 2019 Jul 1;216(7):1682-1699. doi: 10.1084/jem.20181778. Epub 2019 May 29. J Exp Med. 2019. PMID: 31142588 Free PMC article.
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells.
Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, Sidwell T, Kallies A, Chen Z, Nüssing S, Kedzierska K, Mackay LK, McColl SR, Deenick EK, Fairlie DP, McCluskey J, Goodnow CC, Ritchie ME, Belz GT, Naik SH, Pellicci DG, Godfrey DI. Koay HF, et al. Among authors: mackay lk. Sci Immunol. 2019 Nov 22;4(41):eaay6039. doi: 10.1126/sciimmunol.aay6039. Sci Immunol. 2019. PMID: 31757835 Free PMC article.
Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity.
Christo SN, Evrard M, Park SL, Gandolfo LC, Burn TN, Fonseca R, Newman DM, Alexandre YO, Collins N, Zamudio NM, Souza-Fonseca-Guimaraes F, Pellicci DG, Chisanga D, Shi W, Bartholin L, Belz GT, Huntington ND, Lucas A, Lucas M, Mueller SN, Heath WR, Ginhoux F, Speed TP, Carbone FR, Kallies A, Mackay LK. Christo SN, et al. Among authors: mackay lk. Nat Immunol. 2021 Sep;22(9):1140-1151. doi: 10.1038/s41590-021-01004-1. Epub 2021 Aug 23. Nat Immunol. 2021. PMID: 34426691
84 results