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The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs.
Herchenröther A, Gossen S, Friedrich T, Reim A, Daus N, Diegmüller F, Leers J, Sani HM, Gerstner S, Schwarz L, Stellmacher I, Szymkowiak LV, Nist A, Stiewe T, Borggrefe T, Mann M, Mackay JP, Bartkuhn M, Borchers A, Lan J, Hake SB. Herchenröther A, et al. Among authors: mackay jp. Nat Commun. 2023 Jan 28;14(1):472. doi: 10.1038/s41467-023-36114-x. Nat Commun. 2023. PMID: 36709316 Free PMC article.
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.
Link S, Spitzer RMM, Sana M, Torrado M, Völker-Albert MC, Keilhauer EC, Burgold T, Pünzeler S, Low JKK, Lindström I, Nist A, Regnard C, Stiewe T, Hendrich B, Imhof A, Mann M, Mackay JP, Bartkuhn M, Hake SB. Link S, et al. Among authors: mackay jp. Nat Commun. 2018 Oct 16;9(1):4300. doi: 10.1038/s41467-018-06665-5. Nat Commun. 2018. PMID: 30327463 Free PMC article.
The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture.
Low JKK, Silva APG, Sharifi Tabar M, Torrado M, Webb SR, Parker BL, Sana M, Smits C, Schmidberger JW, Brillault L, Jackman MJ, Williams DC Jr, Blobel GA, Hake SB, Shepherd NE, Landsberg MJ, Mackay JP. Low JKK, et al. Among authors: mackay jp. Cell Rep. 2020 Dec 1;33(9):108450. doi: 10.1016/j.celrep.2020.108450. Cell Rep. 2020. PMID: 33264611 Free PMC article.
RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling.
Ullah I, Thölken C, Zhong Y, John M, Rossbach O, Lenz J, Gößringer M, Nist A, Albert L, Stiewe T, Hartmann R, Vázquez O, Chung HR, Mackay JP, Brehm A. Ullah I, et al. Among authors: mackay jp. Cell Rep. 2022 May 31;39(9):110895. doi: 10.1016/j.celrep.2022.110895. Cell Rep. 2022. PMID: 35649367 Free article.
CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation.
Zhong Y, Paudel BP, Ryan DP, Low JKK, Franck C, Patel K, Bedward MJ, Torrado M, Payne RJ, van Oijen AM, Mackay JP. Zhong Y, et al. Among authors: mackay jp. Nat Commun. 2020 Mar 23;11(1):1519. doi: 10.1038/s41467-020-15183-2. Nat Commun. 2020. PMID: 32251276 Free PMC article.
A NuRD for all seasons.
Reid XJ, Low JKK, Mackay JP. Reid XJ, et al. Among authors: mackay jp. Trends Biochem Sci. 2023 Jan;48(1):11-25. doi: 10.1016/j.tibs.2022.06.002. Epub 2022 Jul 4. Trends Biochem Sci. 2023. PMID: 35798615 Review.
224 results