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Transcending the challenge of evolving resistance mechanisms in Pseudomonas aeruginosa through β-lactam-enhancer-mechanism-based cefepime/zidebactam.
Hujer AM, Marshall SH, Mack AR, Hujer KM, Bakthavatchalam YD, Umarkar K, Palwe SR, Takalkar S, Joshi PR, Shrivastava R, Periasamy H, Bhagwat SS, Patel MV, Veeraraghavan B, Bonomo RA. Hujer AM, et al. Among authors: mack ar. mBio. 2023 Oct 27;14(6):e0111823. doi: 10.1128/mbio.01118-23. Online ahead of print. mBio. 2023. PMID: 37889005 Free PMC article.
Imipenem/Relebactam Resistance in Clinical Isolates of Extensively Drug Resistant Pseudomonas aeruginosa: Inhibitor-Resistant β-Lactamases and Their Increasing Importance.
Hujer AM, Bethel CR, Taracila MA, Marshall SH, Rojas LJ, Winkler ML, Painter RE, Domitrovic TN, Watkins RR, Abdelhamed AM, D'Souza R, Mack AR, White RC, Clarke T, Fouts DE, Jacobs MR, Young K, Bonomo RA. Hujer AM, et al. Among authors: mack ar. Antimicrob Agents Chemother. 2022 May 17;66(5):e0179021. doi: 10.1128/aac.01790-21. Epub 2022 Apr 18. Antimicrob Agents Chemother. 2022. PMID: 35435707 Free PMC article.
A comprehensive and contemporary "snapshot" of β-lactamases in carbapenem resistant Acinetobacter baumannii.
Hujer AM, Hujer KM, Leonard DA, Powers RA, Wallar BJ, Mack AR, Taracila MA, Rather PN, Higgins PG, Prati F, Caselli E, Marshall SH, Clarke T, Greco C, Venepally P, Brinkac L, Kreiswirth BN, Fouts DE, Bonomo RA; Antibacterial Resistance Leadership Group (ARLG). Hujer AM, et al. Among authors: mack ar. Diagn Microbiol Infect Dis. 2021 Feb;99(2):115242. doi: 10.1016/j.diagmicrobio.2020.115242. Epub 2020 Oct 16. Diagn Microbiol Infect Dis. 2021. PMID: 33248392 Free PMC article.
Natural protein engineering in the Ω-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas-derived cephalosporinase.
Mack AR, Kumar V, Taracila MA, Mojica MF, O'Shea M, Schinabeck W, Silver G, Hujer AM, Papp-Wallace KM, Chen S, Haider S, Caselli E, Prati F, van den Akker F, Bonomo RA. Mack AR, et al. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0079123. doi: 10.1128/aac.00791-23. Epub 2023 Oct 18. Antimicrob Agents Chemother. 2023. PMID: 37850746 Free PMC article.
A Standard Numbering Scheme for Class C β-Lactamases.
Mack AR, Barnes MD, Taracila MA, Hujer AM, Hujer KM, Cabot G, Feldgarden M, Haft DH, Klimke W, van den Akker F, Vila AJ, Smania A, Haider S, Papp-Wallace KM, Bradford PA, Rossolini GM, Docquier JD, Frère JM, Galleni M, Hanson ND, Oliver A, Plésiat P, Poirel L, Nordmann P, Palzkill TG, Jacoby GA, Bush K, Bonomo RA. Mack AR, et al. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01841-19. doi: 10.1128/AAC.01841-19. Print 2020 Feb 21. Antimicrob Agents Chemother. 2020. PMID: 31712217 Free PMC article.
Genomic heterogeneity underlies multidrug resistance in Pseudomonas aeruginosa: A population-level analysis beyond susceptibility testing.
Rojas LJ, Yasmin M, Benjamino J, Marshall SM, DeRonde KJ, Krishnan NP, Perez F, Colin AA, Cardenas M, Martinez O, Pérez-Cardona A, Rhoads DD, Jacobs MR, LiPuma JJ, Konstan MW, Vila AJ, Smania A, Mack AR, Scott JG, Adams MD, Abbo LM, Bonomo RA. Rojas LJ, et al. Among authors: mack ar. PLoS One. 2022 Mar 31;17(3):e0265129. doi: 10.1371/journal.pone.0265129. eCollection 2022. PLoS One. 2022. PMID: 35358221 Free PMC article.
11 results