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Year Number of Results
2006 1
2007 1
2008 1
2011 1
2012 1
2013 1
2014 3
2015 2
2016 1
2017 1
2018 2
2019 2
2020 4
2021 10
2022 8
2023 4
2024 3

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40 results

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Page 1
Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer.
Popiel D, Stańczak A, Skupińska M, Mikołajczyk A, Stańczak P, Mituła F, Hucz-Kalitowska J, Jastrzębska K, Smuga D, Dominowski J, Delis M, Mulewski K, Pietruś W, Zdżalik-Bielecka D, Dzwonek K, Lamparska-Przybysz M, Yamani A, Olejkowska P, Piórkowska N, Dubiel K, Wieczorek M, Pieczykolan J. Popiel D, et al. Among authors: wieczorek m. Front Oncol. 2024 Jan 12;13:1293728. doi: 10.3389/fonc.2023.1293728. eCollection 2023. Front Oncol. 2024. PMID: 38282676 Free PMC article.
First-in-human study of CPL207280, a novel G-protein-coupled receptor 40/free fatty acid receptor 1 agonist, in healthy volunteers after single and multiple administration.
Bazydło-Guzenda K, Jarus-Dziedzic K, Gierczak-Pachulska A, Buda P, Rudzki PJ, Buś-Kwaśnik K, Juszczyk E, Tratkiewicz E, Rabczenko D, Segiet-Święcicka A, Wieczorek M. Bazydło-Guzenda K, et al. Among authors: wieczorek m. Diabetes Obes Metab. 2024 Apr;26(4):1376-1385. doi: 10.1111/dom.15439. Epub 2024 Jan 11. Diabetes Obes Metab. 2024. PMID: 38204407
Identification and characterization of aptameric inhibitors of human neutrophil elastase.
Malicki S, Książek M, Sochaj Gregorczyk A, Kamińska M, Golda A, Chruścicka B, Mizgalska D, Potempa J, Marti HP, Kozieł J, Wieczorek M, Pieczykolan J, Mydel P, Dubin G. Malicki S, et al. Among authors: wieczorek m. J Biol Chem. 2023 Aug;299(8):104889. doi: 10.1016/j.jbc.2023.104889. Epub 2023 Jun 5. J Biol Chem. 2023. PMID: 37286041 Free PMC article.
The design of experiments (DoE) in optimization of an aerobic flow Pd-catalyzed oxidation of alcohol towards an important aldehyde precursor in the synthesis of phosphatidylinositide 3-kinase inhibitor (CPL302415).
Michałek S, Gurba-Bryśkiewicz L, Maruszak W, Zagozda M, Maj AM, Ochal Z, Dubiel K, Wieczorek M. Michałek S, et al. Among authors: wieczorek m. RSC Adv. 2022 Nov 23;12(52):33605-33611. doi: 10.1039/d2ra07003k. eCollection 2022 Nov 22. RSC Adv. 2022. PMID: 36505705 Free PMC article.
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects.
Matloka M, Janowska S, Pankiewicz P, Kokhanovska S, Kos T, Hołuj M, Rutkowska-Wlodarczyk I, Abramski K, Janicka M, Jakubowski P, Świątkiewicz M, Welniak-Kaminska M, Hucz-Kalitowska J, Dera P, Bojarski L, Grieb P, Popik P, Wieczorek M, Pieczykolan J. Matloka M, et al. Among authors: wieczorek m. Front Pharmacol. 2022 Nov 9;13:999685. doi: 10.3389/fphar.2022.999685. eCollection 2022. Front Pharmacol. 2022. PMID: 36438799 Free PMC article.
Implementation of QbD Approach to the Development of Chromatographic Methods for the Determination of Complete Impurity Profile of Substance on the Preclinical and Clinical Step of Drug Discovery Studies.
Gurba-Bryśkiewicz L, Dawid U, Smuga DA, Maruszak W, Delis M, Szymczak K, Stypik B, Moroz A, Błocka A, Mroczkiewicz M, Dubiel K, Wieczorek M. Gurba-Bryśkiewicz L, et al. Among authors: wieczorek m. Int J Mol Sci. 2022 Sep 14;23(18):10720. doi: 10.3390/ijms231810720. Int J Mol Sci. 2022. PMID: 36142622 Free PMC article.
FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.
Moes-Sosnowska J, Skupinska M, Lechowicz U, Szczepulska-Wojcik E, Skronska P, Rozy A, Stepniewska A, Langfort R, Rudzinski P, Orlowski T, Popiel D, Stanczak A, Wieczorek M, Chorostowska-Wynimko J. Moes-Sosnowska J, et al. Among authors: wieczorek m. Int J Mol Sci. 2022 Sep 10;23(18):10506. doi: 10.3390/ijms231810506. Int J Mol Sci. 2022. PMID: 36142417 Free PMC article.
40 results