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Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2α Inhibitor.
Am J Respir Crit Care Med. 2018 Dec 1;198(11):1423-1434. doi: 10.1164/rccm.201710-2079OC.
Am J Respir Crit Care Med. 2018.
PMID: 29924941
Free PMC article.
Endothelial and Smooth Muscle Cell Interaction via FoxM1 Signaling Mediates Vascular Remodeling and Pulmonary Hypertension.
Dai Z, Zhu MM, Peng Y, Jin H, Machireddy N, Qian Z, Zhang X, Zhao YY.
Dai Z, et al. Among authors: machireddy n.
Am J Respir Crit Care Med. 2018 Sep 15;198(6):788-802. doi: 10.1164/rccm.201709-1835OC.
Am J Respir Crit Care Med. 2018.
PMID: 29664678
Free PMC article.
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Endothelial PHD2 deficiency induces nitrative stress via suppression of caveolin-1 in pulmonary hypertension.
Liu B, Peng Y, Yi D, Machireddy N, Dong D, Ramirez K, Dai J, Vanderpool R, Zhu MM, Dai Z, Zhao YY.
Liu B, et al. Among authors: machireddy n.
Eur Respir J. 2022 Dec 22;60(6):2102643. doi: 10.1183/13993003.02643-2021. Print 2022 Dec.
Eur Respir J. 2022.
PMID: 35798360
Free PMC article.
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Endothelial FoxM1 reactivates aging-impaired endothelial regeneration for vascular repair and resolution of inflammatory lung injury.
Huang X, Zhang X, Machireddy N, Evans CE, Trewartha SD, Hu G, Fang Y, Mutlu GM, Wu D, Zhao YY.
Huang X, et al. Among authors: machireddy n.
Sci Transl Med. 2023 Aug 16;15(709):eabm5755. doi: 10.1126/scitranslmed.abm5755. Epub 2023 Aug 16.
Sci Transl Med. 2023.
PMID: 37585502
Free PMC article.
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The Unexpected Protective Role of Thrombosis in Sepsis-Induced Inflammatory Lung Injury Via Endothelial Alox15.
Evans CE, Zhang X, Machireddy N, Zhao YY.
Evans CE, et al. Among authors: machireddy n.
medRxiv [Preprint]. 2023 Mar 31:2023.03.29.23287934. doi: 10.1101/2023.03.29.23287934.
medRxiv. 2023.
PMID: 37034726
Free PMC article.
Preprint.
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Oxidant-induced cell death and Nrf2-dependent antioxidative response are controlled by Fra-1/AP-1.
Vaz M, Machireddy N, Irving A, Potteti HR, Chevalier K, Kalvakolanu D, Reddy SP.
Vaz M, et al. Among authors: machireddy n.
Mol Cell Biol. 2012 May;32(9):1694-709. doi: 10.1128/MCB.06390-11. Epub 2012 Mar 5.
Mol Cell Biol. 2012.
PMID: 22393254
Free PMC article.
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A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion.
Adiseshaiah P, Vaz M, Machireddy N, Kalvakolanu DV, Reddy SP.
Adiseshaiah P, et al. Among authors: machireddy n.
J Cell Physiol. 2008 Aug;216(2):405-12. doi: 10.1002/jcp.21410.
J Cell Physiol. 2008.
PMID: 18288638
Free PMC article.
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