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Loss of Scar/WAVE complex promotes N-WASP- and FAK-dependent invasion.
Tang H, Li A, Bi J, Veltman DM, Zech T, Spence HJ, Yu X, Timpson P, Insall RH, Frame MC, Machesky LM. Tang H, et al. Among authors: machesky lm. Curr Biol. 2013 Jan 21;23(2):107-17. doi: 10.1016/j.cub.2012.11.059. Epub 2012 Dec 27. Curr Biol. 2013. PMID: 23273897 Free article.
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.
Woodham EF, Paul NR, Tyrrell B, Spence HJ, Swaminathan K, Scribner MR, Giampazolias E, Hedley A, Clark W, Kage F, Marston DJ, Hahn KM, Tait SW, Larue L, Brakebusch CH, Insall RH, Machesky LM. Woodham EF, et al. Among authors: machesky lm. Curr Biol. 2017 Mar 6;27(5):624-637. doi: 10.1016/j.cub.2017.01.033. Epub 2017 Feb 23. Curr Biol. 2017. PMID: 28238662 Free PMC article.
Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.
Reid SE, Kay EJ, Neilson LJ, Henze AT, Serneels J, McGhee EJ, Dhayade S, Nixon C, Mackey JB, Santi A, Swaminathan K, Athineos D, Papalazarou V, Patella F, Román-Fernández Á, ElMaghloob Y, Hernandez-Fernaud JR, Adams RH, Ismail S, Bryant DM, Salmeron-Sanchez M, Machesky LM, Carlin LM, Blyth K, Mazzone M, Zanivan S. Reid SE, et al. Among authors: machesky lm. EMBO J. 2017 Aug 15;36(16):2373-2389. doi: 10.15252/embj.201694912. Epub 2017 Jul 10. EMBO J. 2017. PMID: 28694244 Free PMC article.
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions.
Fort L, Batista JM, Thomason PA, Spence HJ, Whitelaw JA, Tweedy L, Greaves J, Martin KJ, Anderson KI, Brown P, Lilla S, Neilson MP, Tafelmeyer P, Zanivan S, Ismail S, Bryant DM, Tomkinson NCO, Chamberlain LH, Mastick GS, Insall RH, Machesky LM. Fort L, et al. Among authors: machesky lm. Nat Cell Biol. 2018 Oct;20(10):1159-1171. doi: 10.1038/s41556-018-0198-9. Epub 2018 Sep 24. Nat Cell Biol. 2018. PMID: 30250061 Free PMC article.
CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors.
Whitelaw JA, Lilla S, Paul NR, Fort L, Zanivan S, Machesky LM. Whitelaw JA, et al. Among authors: machesky lm. Commun Integr Biol. 2019 Jul 23;12(1):112-118. doi: 10.1080/19420889.2019.1643665. eCollection 2019. Commun Integr Biol. 2019. PMID: 31413787 Free PMC article.
WASP Restricts Active Rac to Maintain Cells' Front-Rear Polarization.
Amato C, Thomason PA, Davidson AJ, Swaminathan K, Ismail S, Machesky LM, Insall RH. Amato C, et al. Among authors: machesky lm. Curr Biol. 2019 Dec 16;29(24):4169-4182.e4. doi: 10.1016/j.cub.2019.10.036. Epub 2019 Nov 27. Curr Biol. 2019. PMID: 31786060 Free PMC article.
The Arp2/3 complex is crucial for colonisation of the mouse skin by melanoblasts.
Papalazarou V, Swaminathan K, Jaber-Hijazi F, Spence H, Lahmann I, Nixon C, Salmeron-Sanchez M, Arnold HH, Rottner K, Machesky LM. Papalazarou V, et al. Among authors: machesky lm. Development. 2020 Nov 15;147(22):dev194555. doi: 10.1242/dev.194555. Development. 2020. PMID: 33028610 Free PMC article.
212 results