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Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial.
Giugliano RP, Pedersen TR, Park JG, De Ferrari GM, Gaciong ZA, Ceska R, Toth K, Gouni-Berthold I, Lopez-Miranda J, Schiele F, Mach F, Ott BR, Kanevsky E, Pineda AL, Somaratne R, Wasserman SM, Keech AC, Sever PS, Sabatine MS; FOURIER Investigators. Giugliano RP, et al. Among authors: mach f. Lancet. 2017 Oct 28;390(10106):1962-1971. doi: 10.1016/S0140-6736(17)32290-0. Epub 2017 Aug 28. Lancet. 2017. PMID: 28859947 Free article. Clinical Trial.
PCSK9 inhibitors.
Gencer B, Lambert G, Mach F. Gencer B, et al. Among authors: mach f. Swiss Med Wkly. 2015 Apr 9;145:w14094. doi: 10.4414/smw.2015.14094. eCollection 2015. Swiss Med Wkly. 2015. PMID: 25856746 Free article. Review.
Prognostic value of PCSK9 levels in patients with acute coronary syndromes.
Gencer B, Montecucco F, Nanchen D, Carbone F, Klingenberg R, Vuilleumier N, Aghlmandi S, Heg D, Räber L, Auer R, Jüni P, Windecker S, Lüscher TF, Matter CM, Rodondi N, Mach F. Gencer B, et al. Among authors: mach f. Eur Heart J. 2016 Feb 7;37(6):546-53. doi: 10.1093/eurheartj/ehv637. Epub 2015 Dec 9. Eur Heart J. 2016. PMID: 26655339 Free article. Clinical Trial.
New concepts in the management of dyslipidaemiaa.
Gencer B, Rodondi N, Mach F. Gencer B, et al. Among authors: mach f. Swiss Med Wkly. 2016 Nov 12;146:w14378. doi: 10.4414/smw.2016.14378. eCollection 2016. Swiss Med Wkly. 2016. PMID: 27878791 Free article.
Design and rationale of the EBBINGHAUS trial: A phase 3, double-blind, placebo-controlled, multicenter study to assess the effect of evolocumab on cognitive function in patients with clinically evident cardiovascular disease and receiving statin background lipid-lowering therapy-A cognitive study of patients enrolled in the FOURIER trial.
Giugliano RP, Mach F, Zavitz K, Kurtz C, Schneider J, Wang H, Keech A, Pedersen TR, Sabatine MS, Sever PS, Honarpour N, Wasserman SM, Ott BR; EBBINGHAUS Investigators. Giugliano RP, et al. Among authors: mach f. Clin Cardiol. 2017 Feb;40(2):59-65. doi: 10.1002/clc.22678. Epub 2017 Feb 16. Clin Cardiol. 2017. PMID: 28207168 Free PMC article. Clinical Trial.
Cognitive Function in a Randomized Trial of Evolocumab.
Giugliano RP, Mach F, Zavitz K, Kurtz C, Im K, Kanevsky E, Schneider J, Wang H, Keech A, Pedersen TR, Sabatine MS, Sever PS, Robinson JG, Honarpour N, Wasserman SM, Ott BR; EBBINGHAUS Investigators. Giugliano RP, et al. Among authors: mach f. N Engl J Med. 2017 Aug 17;377(7):633-643. doi: 10.1056/NEJMoa1701131. N Engl J Med. 2017. PMID: 28813214 Free article. Clinical Trial.
Prevention of Stroke with the Addition of Ezetimibe to Statin Therapy in Patients With Acute Coronary Syndrome in IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).
Bohula EA, Wiviott SD, Giugliano RP, Blazing MA, Park JG, Murphy SA, White JA, Mach F, Van de Werf F, Dalby AJ, White HD, Tershakovec AM, Cannon CP, Braunwald E. Bohula EA, et al. Among authors: mach f. Circulation. 2017 Dec 19;136(25):2440-2450. doi: 10.1161/CIRCULATIONAHA.117.029095. Epub 2017 Sep 30. Circulation. 2017. PMID: 28972004 Clinical Trial.
Eligibility for PCSK9 Inhibitors According to American College of Cardiology (ACC) and European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) Guidelines After Acute Coronary Syndromes.
Gencer B, Koskinas KC, Räber L, Karagiannis A, Nanchen D, Auer R, Carballo D, Carballo S, Klingenberg R, Heg D, Matter CM, Lüscher TF, Rodondi N, Mach F, Windecker S. Gencer B, et al. Among authors: mach f. J Am Heart Assoc. 2017 Nov 9;6(11):e006537. doi: 10.1161/JAHA.117.006537. J Am Heart Assoc. 2017. PMID: 29122809 Free PMC article.
606 results