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Central and peripheral myeloid-derived suppressor cell-like cells are closely related to the clinical severity of multiple sclerosis.
Ortega MC, Lebrón-Galán R, Machín-Díaz I, Naughton M, Pérez-Molina I, García-Arocha J, Garcia-Dominguez JM, Goicoechea-Briceño H, Vila-Del Sol V, Quintanero-Casero V, García-Montero R, Galán V, Calahorra L, Camacho-Toledano C, Martínez-Ginés ML, Fitzgerald DC, Clemente D. Ortega MC, et al. Among authors: machin diaz i. Acta Neuropathol. 2023 Aug;146(2):263-282. doi: 10.1007/s00401-023-02593-x. Epub 2023 May 27. Acta Neuropathol. 2023. PMID: 37243699 Free PMC article.
Peripheral myeloid-derived suppressor cells are good biomarkers of the efficacy of fingolimod in multiple sclerosis.
Camacho-Toledano C, Machín-Díaz I, Calahorra L, Cabañas-Cotillas M, Otaegui D, Castillo-Triviño T, Villar LM, Costa-Frossard L, Comabella M, Midaglia L, García-Domínguez JM, García-Arocha J, Ortega MC, Clemente D. Camacho-Toledano C, et al. Among authors: machin diaz i. J Neuroinflammation. 2022 Nov 19;19(1):277. doi: 10.1186/s12974-022-02635-3. J Neuroinflammation. 2022. PMID: 36403026 Free PMC article.
NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
Malhotra S, Costa C, Eixarch H, Keller CW, Amman L, Martínez-Banaclocha H, Midaglia L, Sarró E, Machín-Díaz I, Villar LM, Triviño JC, Oliver-Martos B, Parladé LN, Calvo-Barreiro L, Matesanz F, Vandenbroeck K, Urcelay E, Martínez-Ginés ML, Tejeda-Velarde A, Fissolo N, Castilló J, Sanchez A, Robertson AAB, Clemente D, Prinz M, Pelegrin P, Lünemann JD, Espejo C, Montalban X, Comabella M. Malhotra S, et al. Among authors: machin diaz i. Brain. 2020 May 1;143(5):1414-1430. doi: 10.1093/brain/awaa084. Brain. 2020. PMID: 32282893 Free article.
The proportion of myeloid-derived suppressor cells in the spleen is related to the severity of the clinical course and tissue damage extent in a murine model of multiple sclerosis.
Melero-Jerez C, Alonso-Gómez A, Moñivas E, Lebrón-Galán R, Machín-Díaz I, de Castro F, Clemente D. Melero-Jerez C, et al. Among authors: machin diaz i. Neurobiol Dis. 2020 Jul;140:104869. doi: 10.1016/j.nbd.2020.104869. Epub 2020 Apr 9. Neurobiol Dis. 2020. PMID: 32278882 Free article.
The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-β treatment in a murine model of multiple sclerosis.
Melero-Jerez C, Suardíaz M, Lebrón-Galán R, Marín-Bañasco C, Oliver-Martos B, Machín-Díaz I, Fernández Ó, de Castro F, Clemente D. Melero-Jerez C, et al. Among authors: machin diaz i. Neurobiol Dis. 2019 Jul;127:13-31. doi: 10.1016/j.nbd.2019.02.014. Epub 2019 Feb 21. Neurobiol Dis. 2019. PMID: 30798007 Free article.