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Technical Advance: Function and efficacy of an {alpha}4-integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis.
Murphy CT, Moloney G, Macsharry J, Haynes A, Faivre E, Quinlan A, McLean PG, Lee K, O'Mahony L, Shanahan F, Melgar S, Nally K. Murphy CT, et al. Among authors: macsharry j. J Leukoc Biol. 2010 Dec;88(6):1271-8. doi: 10.1189/jlb.0909627. Epub 2010 Aug 25. J Leukoc Biol. 2010. PMID: 20739616
Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50.
Canavan M, McCarthy C, Larbi NB, Dowling JK, Collins L, O'Sullivan F, Hurley G, Murphy C, Quinlan A, Moloney G, Darby T, MacSharry J, Kagechika H, Moynagh P, Melgar S, Loscher CE. Canavan M, et al. Among authors: macsharry j. Innate Immun. 2014 Oct;20(7):675-87. doi: 10.1177/1753425913501915. Epub 2013 Sep 17. Innate Immun. 2014. PMID: 24045337 Free article.
The influence of rosuvastatin on the gastrointestinal microbiota and host gene expression profiles.
Nolan JA, Skuse P, Govindarajan K, Patterson E, Konstantinidou N, Casey PG, MacSharry J, Shanahan F, Stanton C, Hill C, Cotter PD, Joyce SA, Gahan CGM. Nolan JA, et al. Among authors: macsharry j. Am J Physiol Gastrointest Liver Physiol. 2017 May 1;312(5):G488-G497. doi: 10.1152/ajpgi.00149.2016. Epub 2017 Feb 16. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28209601 Free article.
DNA sensor-associated type I interferon signaling is increased in ulcerative colitis and induces JAK-dependent inflammatory cell death in colonic organoids.
Flood P, Fanning A, Woznicki JA, Crowley T, Christopher A, Vaccaro A, Houston A, McSweeney S, Ross S, Hogan A, Brint E, Skowyra A, Bustamante M, Ambrose M, Moloney G, MacSharry J, Hammarström ML, Hurley M, Fitzgibbons C, Quigley EMM, Shanahan F, Zulquernain SA, McCarthy J, Dodson GS, Dabbagh K, McRae BL, Melgar S, Nally K. Flood P, et al. Among authors: macsharry j. Am J Physiol Gastrointest Liver Physiol. 2022 Nov 1;323(5):G439-G460. doi: 10.1152/ajpgi.00104.2022. Epub 2022 Sep 27. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 36165492 Free article.
64 results