MacKenzie KR - Search Results

1

Acetylation Disfavors Tau Phase Separation.

Ferreon JC, Jain A, Choi KJ, Tsoi PS, MacKenzie KR, Jung SY, Ferreon AC. Ferreon JC, et al. Among authors: mackenzie kr. Int J Mol Sci. 2018 May 4;19(5):1360. doi: 10.3390/ijms19051360. Int J Mol Sci. 2018. PMID: 29734651 Free PMC article.

2

The N-Terminal Domain of ALS-Linked TDP-43 Assembles without Misfolding.

Tsoi PS, Choi KJ, Leonard PG, Sizovs A, Moosa MM, MacKenzie KR, Ferreon JC, Ferreon ACM. Tsoi PS, et al. Among authors: mackenzie kr. Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12590-12593. doi: 10.1002/anie.201706769. Epub 2017 Sep 5. Angew Chem Int Ed Engl. 2017. PMID: 28833982

3

Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine.

MacKenzie KR, Zhao M, Barzi M, Wang J, Bissig KD, Maletic-Savatic M, Jung SY, Li F. MacKenzie KR, et al. Eur J Pharm Sci. 2020 Oct 1;153:105488. doi: 10.1016/j.ejps.2020.105488. Epub 2020 Jul 23. Eur J Pharm Sci. 2020. PMID: 32712217 Free PMC article.

4

Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization.

Sharma R, Choi KJ, Quan MD, Sharma S, Sankaran B, Park H, LaGrone A, Kim JJ, MacKenzie KR, Ferreon ACM, Kim C, Ferreon JC. Sharma R, et al. Among authors: mackenzie kr. Nat Commun. 2021 Sep 22;12(1):5579. doi: 10.1038/s41467-021-25761-7. Nat Commun. 2021. PMID: 34552088 Free PMC article.

5

Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice.

Qin X, Hakenjos JM, MacKenzie KR, Barzi M, Chavan H, Nyshadham P, Wang J, Jung SY, Guner JZ, Chen S, Guo L, Krishnamurthy P, Bissig KD, Palmer S, Matzuk MM, Li F. Qin X, et al. Among authors: mackenzie kr. Drug Metab Dispos. 2022 Feb;50(2):128-139. doi: 10.1124/dmd.121.000633. Epub 2021 Nov 16. Drug Metab Dispos. 2022. PMID: 34785568 Free PMC article.

6

Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC-MS-Based Metabolomic Approaches.

Qin X, Wang Y, MacKenzie KR, Hakenjos JM, Chen S, Khalil SM, Jung SY, Young DW, Guo L, Li F. Qin X, et al. Among authors: mackenzie kr. Chem Res Toxicol. 2023 Aug 21;36(8):1427-1438. doi: 10.1021/acs.chemrestox.3c00164. Epub 2023 Aug 2. Chem Res Toxicol. 2023. PMID: 37531179 Free PMC article.

7

The Tail-End Is Only the Beginning: NMR Study Reveals a Membrane-Bound State of BCL-XL.

Hill RB, MacKenzie KR, Harwig MC. Hill RB, et al. Among authors: mackenzie kr. J Mol Biol. 2015 Jul 3;427(13):2257-61. doi: 10.1016/j.jmb.2015.04.005. Epub 2015 Apr 18. J Mol Biol. 2015. PMID: 25896456 No abstract available.

8

Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix-helix interactions.

Sulistijo ES, MacKenzie KR. Sulistijo ES, et al. Among authors: mackenzie kr. J Mol Biol. 2006 Dec 15;364(5):974-90. doi: 10.1016/j.jmb.2006.09.065. Epub 2006 Sep 29. J Mol Biol. 2006. PMID: 17049556

9

Changes in apparent free energy of helix-helix dimerization in a biological membrane due to point mutations.

Duong MT, Jaszewski TM, Fleming KG, MacKenzie KR. Duong MT, et al. Among authors: mackenzie kr. J Mol Biol. 2007 Aug 10;371(2):422-34. doi: 10.1016/j.jmb.2007.05.026. Epub 2007 May 18. J Mol Biol. 2007. PMID: 17570394 Free PMC article.

10

Intermonomer hydrogen bonds enhance GxxxG-driven dimerization of the BNIP3 transmembrane domain: roles for sequence context in helix-helix association in membranes.

Lawrie CM, Sulistijo ES, MacKenzie KR. Lawrie CM, et al. Among authors: mackenzie kr. J Mol Biol. 2010 Mar 5;396(4):924-36. doi: 10.1016/j.jmb.2009.12.023. Epub 2009 Dec 21. J Mol Biol. 2010. PMID: 20026130 Free PMC article.

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