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Tau protein liquid-liquid phase separation can initiate tau aggregation.
Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C, Roe AD, Fan Z, Molliex AM, Hernandez-Vega A, Muller D, Hyman AA, Mandelkow E, Taylor JP, Hyman BT. Wegmann S, et al. Among authors: mackenzie d. EMBO J. 2018 Apr 3;37(7):e98049. doi: 10.15252/embj.201798049. Epub 2018 Feb 22. EMBO J. 2018. PMID: 29472250 Free PMC article.
Persistent repression of tau in the brain using engineered zinc finger protein transcription factors.
Wegmann S, DeVos SL, Zeitler B, Marlen K, Bennett RE, Perez-Rando M, MacKenzie D, Yu Q, Commins C, Bannon RN, Corjuc BT, Chase A, Diez L, Nguyen HB, Hinkley S, Zhang L, Goodwin A, Ledeboer A, Lam S, Ankoudinova I, Tran H, Scarlott N, Amora R, Surosky R, Miller JC, Robbins AB, Rebar EJ, Urnov FD, Holmes MC, Pooler AM, Riley B, Zhang HS, Hyman BT. Wegmann S, et al. Among authors: mackenzie d. Sci Adv. 2021 Mar 19;7(12):eabe1611. doi: 10.1126/sciadv.abe1611. Print 2021 Mar. Sci Adv. 2021. PMID: 33741591 Free PMC article.
Elucidation of the molecular mechanism of the breakage-fusion-bridge (BFB) cycle using a CRISPR-dCas9 cellular model.
Singh M, Raseley K, Perez AM, MacKenzie D, Kosiyatrakul ST, Desai S, Batista N, Guru N, Loomba KK, Abid HZ, Wang Y, Udo-Bellner L, Stout RF, Schildkraut CL, Xiao M, Zhang D. Singh M, et al. Among authors: mackenzie d. bioRxiv [Preprint]. 2024 Apr 3:2024.04.03.587951. doi: 10.1101/2024.04.03.587951. bioRxiv. 2024. PMID: 38617299 Free PMC article. Preprint.
Neurodevelopmental profiles of 4-year-olds in the Navajo Birth Cohort Study.
Rennie BJ, Bishop SL, Leventhal BL, Zheng S, Geib E, Kim YS, Burnette C, Salzman E, Nozadi SS, Kim H, Ence W, Park M, Ghods S, Welch M, MacKenzie D, Lewis JL. Rennie BJ, et al. Among authors: mackenzie d. JAACAP Open. 2023 Nov;1(3):184-195. doi: 10.1016/j.jaacop.2023.06.003. Epub 2023 Jul 5. JAACAP Open. 2023. PMID: 38239266 Free PMC article.
C-CASE 2023: Promoting Excellence in Surgical Education: Canadian Conference for the Advancement of Surgical Education, Oct. 12-13, 2023, Montréal, Quebec.
Sioufi J, Hall B, Antel R, Moussa S, Subasri M, Fakih M, Islam N, Hamdy RC, Chopra S, Harley JM, Keuhl A, Bassilious E, Sherbino J, Bilgic E, Bondok MS, Bondok M, Martel L, Law C, Posel N, Fleiszer D, Daud A, Hauer T, Carr-Pries N, Hali K, Wolfstadt J, Ferguson P, Ghasroddashti A, Sorefan-Mangou F, Del Fernandes R, Williams E, Choi K, Zevin B, Patterson ED, Kirupaharan S, Mann S, Winthrop A, Zevin B, Bondok M, Ghanmi N, Etherington C, Saddiki Y, Lefebvre I, Berthelot P, Dion PM, Raymond B, Seguin J, Sekhavati P, Islam S, Boet S, Tee T, Pachchigar P, Tarabay B, Yilmaz R, Hamdan NA, Agu C, Almansouri A, Harley J, Del Maestro R, Bondok M, Bondok MS, Nguyen AX, Law C, Nathoo N, Bakshi N, Ahuja N, Damji KF, Grewal K, Azher S, Moreno M, Pekrun R, Wiseman J, Fried GM, Lajoie S, Brydges R, Hadwin A, Sun NZ, Khalil E, Harley JM, Nguyen EL, Patel P, Muaddi H, Rukavina N, Bucur R, Shwaartz C, Islam N, Moussa S, Subasri M, Fakih M, Hamdy RC, Wong E, Tewari A, Brydges R, Louridas M, Balaji S, Patel P, Muaddi H, Gaebe K, Luzzi C, Kay A, Rukavina N, Selzner M, Reichman T, Shwaartz C, Balaji S, Muaddi H, Shahabinezhad A, Patel P, Rukavina N, Reichman T, Jayaraman S, Shwaartz C, Nashed J, Ramelli … See abstract for full author list ➔ Sioufi J, et al. Among authors: mackenzie d. Can J Surg. 2023 Dec 8;66(6 Suppl 2):S137-S150. doi: 10.1503/cjs.014523. Print 2023 Nov-Dec. Can J Surg. 2023. PMID: 38065582 Free PMC article. No abstract available.
Opportunities for Examining Child Health Impacts of Early-Life Nutrition in the ECHO Program: Maternal and Child Dietary Intake Data from Pregnancy to Adolescence.
Bragg MG, Westlake M, Alshawabkeh AN, Bekelman TA, Camargo CA Jr, Catellier DJ, Comstock SS, Dabelea D, Dunlop AL, Hedderson MM, Hockett CW, Karagas MR, Keenan K, Kelly NR, Kerver JM, MacKenzie D, Mahabir S, Maldonado LE, McCormack LA, Melough MM, Mueller NT, Nelson ME, O'Connor TG, Oken E, O'Shea TM, Switkowski KM, Sauder KA, Wright RJ, Wright RO, Zhang X, Zhu Y, Lyall K; program collaborators for Environmental influences on Child Health Outcomes. Bragg MG, et al. Among authors: mackenzie d. Curr Dev Nutr. 2023 Oct 23;7(11):102019. doi: 10.1016/j.cdnut.2023.102019. eCollection 2023 Nov. Curr Dev Nutr. 2023. PMID: 38035205 Free PMC article.
898 results