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The pathogenesis of mesothelioma is driven by a dysregulated translatome.
Grosso S, Marini A, Gyuraszova K, Voorde JV, Sfakianos A, Garland GD, Tenor AR, Mordue R, Chernova T, Morone N, Sereno M, Smith CP, Officer L, Farahmand P, Rooney C, Sumpton D, Das M, Teodósio A, Ficken C, Martin MG, Spriggs RV, Sun XM, Bushell M, Sansom OJ, Murphy D, MacFarlane M, Le Quesne JPC, Willis AE. Grosso S, et al. Among authors: macfarlane m. Nat Commun. 2021 Aug 13;12(1):4920. doi: 10.1038/s41467-021-25173-7. Nat Commun. 2021. PMID: 34389715 Free PMC article.
Initiation of Apaf-1 translation by internal ribosome entry.
Coldwell MJ, Mitchell SA, Stoneley M, MacFarlane M, Willis AE. Coldwell MJ, et al. Among authors: macfarlane m. Oncogene. 2000 Feb 17;19(7):899-905. doi: 10.1038/sj.onc.1203407. Oncogene. 2000. PMID: 10702798
Caspase activation inhibits proteasome function during apoptosis.
Sun XM, Butterworth M, MacFarlane M, Dubiel W, Ciechanover A, Cohen GM. Sun XM, et al. Among authors: macfarlane m. Mol Cell. 2004 Apr 9;14(1):81-93. doi: 10.1016/s1097-2765(04)00156-x. Mol Cell. 2004. PMID: 15068805 Free article.
A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.
Horvilleur E, Sbarrato T, Hill K, Spriggs RV, Screen M, Goodrem PJ, Sawicka K, Chaplin LC, Touriol C, Packham G, Potter KN, Dirnhofer S, Tzankov A, Dyer MJ, Bushell M, MacFarlane M, Willis AE. Horvilleur E, et al. Among authors: macfarlane m. Leukemia. 2014 May;28(5):1092-102. doi: 10.1038/leu.2013.295. Epub 2013 Oct 18. Leukemia. 2014. PMID: 24135829 Free PMC article.
Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.
Chernova T, Sun XM, Powley IR, Galavotti S, Grosso S, Murphy FA, Miles GJ, Cresswell L, Antonov AV, Bennett J, Nakas A, Dinsdale D, Cain K, Bushell M, Willis AE, MacFarlane M. Chernova T, et al. Among authors: macfarlane m. Cell Death Differ. 2016 Jul;23(7):1152-64. doi: 10.1038/cdd.2015.165. Epub 2016 Feb 19. Cell Death Differ. 2016. PMID: 26891694 Free PMC article.
348 results