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Dietary lipid is largely deposited in skin and rapidly affects insulating properties.
Riley N, Kasza I, Barrett-Wilt G, Michaud J, Jain R, Trautman ME, Simcox JA, Yen CE, MacDougald OA, Lamming DW, Alexander CM. Riley N, et al. Among authors: macdougald oa. Res Sq [Preprint]. 2024 Feb 22:rs.3.rs-3957002. doi: 10.21203/rs.3.rs-3957002/v1. Res Sq. 2024. PMID: 38464106 Free PMC article. Preprint.
Dermal white adipose tissue: a new component of the thermogenic response.
Alexander CM, Kasza I, Yen CL, Reeder SB, Hernando D, Gallo RL, Jahoda CA, Horsley V, MacDougald OA. Alexander CM, et al. Among authors: macdougald oa. J Lipid Res. 2015 Nov;56(11):2061-9. doi: 10.1194/jlr.R062893. Epub 2015 Sep 24. J Lipid Res. 2015. PMID: 26405076 Free PMC article. Review.
Evaporative cooling provides a major metabolic energy sink.
Kasza I, Adler D, Nelson DW, Eric Yen CL, Dumas S, Ntambi JM, MacDougald OA, Hernando D, Porter WP, Best FA, Alexander CM. Kasza I, et al. Among authors: macdougald oa. Mol Metab. 2019 Sep;27:47-61. doi: 10.1016/j.molmet.2019.06.023. Epub 2019 Jul 1. Mol Metab. 2019. PMID: 31302039 Free PMC article.
Syndecan-1 is required to maintain intradermal fat and prevent cold stress.
Kasza I, Suh Y, Wollny D, Clark RJ, Roopra A, Colman RJ, MacDougald OA, Shedd TA, Nelson DW, Yen MI, Yen CL, Alexander CM. Kasza I, et al. Among authors: macdougald oa. PLoS Genet. 2014 Aug 7;10(8):e1004514. doi: 10.1371/journal.pgen.1004514. eCollection 2014 Aug. PLoS Genet. 2014. PMID: 25101993 Free PMC article.
Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance.
Bozadjieva-Kramer N, Shin JH, Li Z, Rupp AC, Miller N, Kernodle S, Lanthier N, Henry P, Seshadri N, Myronovych A, MacDougald OA, O'Rourke RW, Kohli R, Burant CF, Rothberg AE, Seeley RJ. Bozadjieva-Kramer N, et al. Among authors: macdougald oa. JCI Insight. 2024 Apr 8;9(7):e174164. doi: 10.1172/jci.insight.174164. JCI Insight. 2024. PMID: 38587078 Free article.
Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon RC, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung JN, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mori H, et al. Among authors: macdougald oa. Mol Metab. 2024 May;83:101916. doi: 10.1016/j.molmet.2024.101916. Epub 2024 Mar 14. Mol Metab. 2024. PMID: 38492843 Free PMC article.
SCD1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
Mori H, Peterson SK, Simmermon R, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung J, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mori H, et al. Among authors: macdougald oa. bioRxiv [Preprint]. 2023 Oct 27:2023.10.27.564376. doi: 10.1101/2023.10.27.564376. bioRxiv. 2023. PMID: 37961537 Free PMC article. Updated. Preprint.
Deciphering the Clinical Presentations in LMNA-related Lipodystrophy: Report of 115 Cases and a Systematic Review.
Besci O, Foss de Freitas MC, Guidorizzi NR, Guler MC, Gilio D, Maung JN, Schill RL, Hoose KS, Obua BN, Gomes AD, Yıldırım Şimşir I, Demir K, Akinci B, MacDougald OA, Oral EA. Besci O, et al. Among authors: macdougald oa. J Clin Endocrinol Metab. 2024 Feb 20;109(3):e1204-e1224. doi: 10.1210/clinem/dgad606. J Clin Endocrinol Metab. 2024. PMID: 37843397
173 results