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Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial.
Williams B, MacDonald TM, Morant S, Webb DJ, Sever P, McInnes G, Ford I, Cruickshank JK, Caulfield MJ, Salsbury J, Mackenzie I, Padmanabhan S, Brown MJ; British Hypertension Society's PATHWAY Studies Group. Williams B, et al. Among authors: macdonald tm. Lancet. 2015 Nov 21;386(10008):2059-2068. doi: 10.1016/S0140-6736(15)00257-3. Epub 2015 Sep 20. Lancet. 2015. PMID: 26414968 Free PMC article. Clinical Trial.
Effects of valsartan compared to amlodipine on preventing type 2 diabetes in high-risk hypertensive patients: the VALUE trial.
Kjeldsen SE, Julius S, Mancia G, McInnes GT, Hua T, Weber MA, Coca A, Ekman S, Girerd X, Jamerson K, Larochelle P, MacDonald TM, Schmieder RE, Schork MA, Stolt P, Viskoper R, Widimský J, Zanchetti A; VALUE Trial Investigators. Kjeldsen SE, et al. Among authors: macdonald tm. J Hypertens. 2006 Jul;24(7):1405-12. doi: 10.1097/01.hjh.0000234122.55895.5b. J Hypertens. 2006. PMID: 16794491 Clinical Trial.
Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study.
Parthasarathy HK, Alhashmi K, McMahon AD, Struthers AD, Connell JM, McInnes GT, Ford I, MacDonald TM. Parthasarathy HK, et al. Among authors: macdonald tm. BMC Cardiovasc Disord. 2007 May 9;7:14. doi: 10.1186/1471-2261-7-14. BMC Cardiovasc Disord. 2007. PMID: 17490489 Free PMC article. Clinical Trial.
The unintended consequences of clinical trials regulations.
McMahon AD, Conway DI, Macdonald TM, McInnes GT. McMahon AD, et al. Among authors: macdonald tm. PLoS Med. 2009 Nov;3(11):e1000131. doi: 10.1371/journal.pmed.1000131. Epub 2009 Nov 17. PLoS Med. 2009. PMID: 19918557 Free PMC article.
Treatment of osteoarthritis in hypertensive patients.
Mackenzie IS, MacDonald TM. Mackenzie IS, et al. Among authors: macdonald tm. Expert Opin Pharmacother. 2010 Feb;11(3):393-403. doi: 10.1517/14656560903496422. Expert Opin Pharmacother. 2010. PMID: 20059368 Review.
389 results