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G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model.
Huang Y, Rafael Guimarães T, Todd N, Ferguson C, Weiss KM, Stauffer FR, McDermott B, Hurtle BT, Saito T, Saido TC, MacDonald ML, Homanics GE, Thathiah A. Huang Y, et al. Among authors: macdonald ml. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2204828119. doi: 10.1073/pnas.2204828119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161942 Free PMC article.
MAP2 is differentially phosphorylated in schizophrenia, altering its function.
Grubisha MJ, Sun X, MacDonald ML, Garver M, Sun Z, Paris KA, Patel DS, DeGiosio RA, Lewis DA, Yates NA, Camacho C, Homanics GE, Ding Y, Sweet RA. Grubisha MJ, et al. Among authors: macdonald ml. Mol Psychiatry. 2021 Sep;26(9):5371-5388. doi: 10.1038/s41380-021-01034-z. Epub 2021 Feb 1. Mol Psychiatry. 2021. PMID: 33526823 Free PMC article.
Psychosis in Alzheimer's Disease Is Associated With Increased Excitatory Neuron Vulnerability and Post-transcriptional Mechanisms Altering Synaptic Protein Levels.
DeChellis-Marks MR, Wei Y, Ding Y, Wolfe CM, Krivinko JM, MacDonald ML, Lopez OL, Sweet RA, Kofler J. DeChellis-Marks MR, et al. Among authors: macdonald ml. Front Neurol. 2022 Mar 2;13:778419. doi: 10.3389/fneur.2022.778419. eCollection 2022. Front Neurol. 2022. PMID: 35309563 Free PMC article.
More than a marker: potential pathogenic functions of MAP2.
DeGiosio RA, Grubisha MJ, MacDonald ML, McKinney BC, Camacho CJ, Sweet RA. DeGiosio RA, et al. Among authors: macdonald ml. Front Mol Neurosci. 2022 Sep 16;15:974890. doi: 10.3389/fnmol.2022.974890. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36187353 Free PMC article.
Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease.
Sweet RA, MacDonald ML, Kirkwood CM, Ding Y, Schempf T, Jones-Laughner J, Kofler J, Ikonomovic MD, Lopez OL, Garver ME, Fitz NF, Koldamova R, Yates NA. Sweet RA, et al. Among authors: macdonald ml. Mol Cell Proteomics. 2016 Jul;15(7):2252-62. doi: 10.1074/mcp.M115.056580. Epub 2016 Apr 21. Mol Cell Proteomics. 2016. PMID: 27103636 Free PMC article.
105 results