MacDonald GC - Search Results

1

DeBouganin Diabody Fusion Protein Overcomes Drug Resistance to ADCs Comprised of Anti-Microtubule Agents.

Chooniedass S, Dillon RL, Premsukh A, Hudson PJ, Adams GP, MacDonald GC, Cizeau J. Chooniedass S, et al. Among authors: macdonald gc. Molecules. 2016 Dec 17;21(12):1741. doi: 10.3390/molecules21121741. Molecules. 2016. PMID: 27999336 Free PMC article.

2

Trastuzumab-deBouganin Conjugate Overcomes Multiple Mechanisms of T-DM1 Drug Resistance.

Dillon RL, Chooniedass S, Premsukh A, Adams GP, Entwistle J, MacDonald GC, Cizeau J. Dillon RL, et al. Among authors: macdonald gc. J Immunother. 2016 Apr;39(3):117-26. doi: 10.1097/CJI.0000000000000115. J Immunother. 2016. PMID: 26938945

3

Engineering and biological characterization of VB6-845, an anti-EpCAM immunotoxin containing a T-cell epitope-depleted variant of the plant toxin bouganin.

Cizeau J, Grenkow DM, Brown JG, Entwistle J, MacDonald GC. Cizeau J, et al. Among authors: macdonald gc. J Immunother. 2009 Jul-Aug;32(6):574-84. doi: 10.1097/CJI.0b013e3181a6981c. J Immunother. 2009. PMID: 19483652

4

Fusogenics: a recombinant immunotoxin-based screening platform to select internalizing tumor-specific antibody fragments.

Cizeau J, Torres MG, Cowling SG, Stibbard S, Premsukh A, Entwistle J, MacDonald GC. Cizeau J, et al. Among authors: macdonald gc. J Biomol Screen. 2011 Jan;16(1):90-100. doi: 10.1177/1087057110387425. Epub 2010 Dec 3. J Biomol Screen. 2011. PMID: 21131595

5

Preclinical evaluation of VB6-845: an anti-EpCAM immunotoxin with reduced immunogenic potential.

Entwistle J, Brown JG, Chooniedass S, Cizeau J, MacDonald GC. Entwistle J, et al. Among authors: macdonald gc. Cancer Biother Radiopharm. 2012 Nov;27(9):582-92. doi: 10.1089/cbr.2012.1200.271. Epub 2012 Aug 2. Cancer Biother Radiopharm. 2012. PMID: 22856424

6

Development of a GMP Phase III purification process for VB4-845, an immunotoxin expressed in E. coli using high cell density fermentation.

Premsukh A, Lavoie JM, Cizeau J, Entwistle J, MacDonald GC. Premsukh A, et al. Among authors: macdonald gc. Protein Expr Purif. 2011 Jul;78(1):27-37. doi: 10.1016/j.pep.2011.03.009. Epub 2011 Mar 21. Protein Expr Purif. 2011. PMID: 21421055

7

Human Leukocyte Antigen-Presented Macrophage Migration Inhibitory Factor Is a Surface Biomarker and Potential Therapeutic Target for Ovarian Cancer.

Patterson AM, Kaabinejadian S, McMurtrey CP, Bardet W, Jackson KW, Zuna RE, Husain S, Adams GP, MacDonald G, Dillon RL, Ames H, Buchli R, Hawkins OE, Weidanz JA, Hildebrand WH. Patterson AM, et al. Mol Cancer Ther. 2016 Feb;15(2):313-22. doi: 10.1158/1535-7163.MCT-15-0658. Epub 2015 Dec 30. Mol Cancer Ther. 2016. PMID: 26719579 Free PMC article.

8

Preclinical assessment of an anti-EpCAM immunotoxin: locoregional delivery provides a safer alternative to systemic administration.

Brown J, Rasamoelisolo M, Spearman M, Bosc D, Cizeau J, Entwistle J, MacDonald GC. Brown J, et al. Among authors: macdonald gc. Cancer Biother Radiopharm. 2009 Aug;24(4):477-87. doi: 10.1089/cbr.2008.0579. Cancer Biother Radiopharm. 2009. PMID: 19694583

9

A Phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCGrefractory and BCG-intolerant patients.

Kowalski M, Entwistle J, Cizeau J, Niforos D, Loewen S, Chapman W, MacDonald GC. Kowalski M, et al. Among authors: macdonald gc. Drug Des Devel Ther. 2010 Nov 15;4:313-20. doi: 10.2147/DDDT.S14071. Drug Des Devel Ther. 2010. PMID: 21151619 Free PMC article. Clinical Trial.

10

A phase I clinical study of VB4-845: weekly intratumoral administration of an anti-EpCAM recombinant fusion protein in patients with squamous cell carcinoma of the head and neck.

MacDonald GC, Rasamoelisolo M, Entwistle J, Cizeau J, Bosc D, Cuthbert W, Kowalski M, Spearman M, Glover N. MacDonald GC, et al. Drug Des Devel Ther. 2009 Feb 6;2:105-14. doi: 10.2147/dddt.s3442. Drug Des Devel Ther. 2009. PMID: 19920898 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

31 results

Search Page